Intra-droplet particle enrichment in a focused acoustic field

Qin, Xianming; Wang, Hairong; Wei, Xueyong

doi:10.1039/d0ra01512a

Cited by 10 publications

(6 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Capture and enrichment of particles or cells are crucial in biomedical and biochemical assays. [ 30 ] We also demonstrated the potential of the light‐fueled water droplet for particle capture and transportation in a complex environment. For example, the target polystyrene particles were placed on the upper layer, while the water droplet was placed on the lower layer.…”

Section: Resultsmentioning

confidence: 99%

Light‐Fueled Submarine‐Like Droplet

et al. 2022

View full text Add to dashboard Cite

Flexibly and precisely manipulating 3D droplet transportation is a fundamental challenge for broad implications in diagnostics, drug delivery, bioengineering, etc. Herein, a light method is developed for manipulating a droplet to make it behave like a submarine. This light method enables flexible 3D transportation, stable suspension, and floating of a droplet, which can be freely altered. It is demonstrated that the localized photothermal effect induced thermocapillary flow in the water droplet/oil phase is responsible for energizing and manipulating the droplet. With such remarkable motility, the light-fueled submarine-like droplet successfully realizes various functions such as the acid-base detection, particle capture and transportation, and target crystal collection, dissolution and transportation. It is demonstrated that the light-fueled submarine-like droplet shows promising perspective for long-sought precise droplet manipulation in various applications.

show abstract

Section: Resultsmentioning

confidence: 99%

Light‐Fueled Submarine‐Like Droplet

et al. 2022

View full text Add to dashboard Cite

show abstract

“…In fact, in addition to the droplets, manipulating the transport of particles or cells is also crucial in biomedical and biochemical assays. 25 Since the smart strategy proposed in this study mainly relies on the surface tension gradient generated by the decanol liquid lenses, it can also be applied to objects other than droplets. Herein, we also show a stable transportation of solid particles by the liquid lenses (Fig.…”

Section: Resultsmentioning

confidence: 99%

Micro-object manipulation by decanol liquid lenses

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Droplet-based fluidic chip has attracted widespread attention in the fields of biology and chemistry in recent years [ 38 ], as droplets provide a clean and stable experimental environment by acting as a separate reservoir [ 26 ]. In the experimental process, PZT transducer (7BB-20-6L0, Murata, Tokyo, Japan) was glued to the substrate.…”

Section: Methodsmentioning

confidence: 99%

“…High frequency (~MHz) SAW often transport particles by generating streaming flow within the fluid [ 24 , 25 ]. Focused IDTs can achieve in-droplet particle concentration continuously by producing powerful vortex streaming [ 26 ]. Slanted IDTs enable broad-band frequency SAW excitation, and the vortex streaming induced in the droplet can be used for centrifugation to achieve the enrichment of nanoparticles [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

Concentration of Microparticles Using Flexural Acoustic Wave in Sessile Droplets

Peng

Zhou

et al. 2022

Sensors

View full text Add to dashboard Cite

Acoustic manipulation of microparticles and cells has attracted growing interest in biomedical applications. In particular, the use of acoustic waves to concentrate particles plays an important role in enhancing the detection process by biosensors. Here, we demonstrated microparticle concentration within sessile droplets placed on the hydrophobic surface using the flexural wave. The design benefits from streaming flow induced by the Lamb wave propagated in the glass waveguide to manipulate particles in the droplets. Microparticles will be concentrated at the central area of the droplet adhesion plane based on the balance among the streaming drag force, gravity, and buoyancy at the operating frequency. We experimentally demonstrated the concentration of particles of various sizes and tumor cells. Using numerical simulation, we predicted the acoustic pressure and streaming flow pattern within the droplet and characterized the underlying physical mechanisms for particle motion. The design is more suitable for micron-sized particle preparation, and it can be valuable for various biological, chemical, and medical applications.

show abstract

Intra-droplet particle enrichment in a focused acoustic field

Abstract: Particle enrichment is an important preparation/collection process in biomedical and biochemical experiments, but enrichment in droplets is harder to realize than in continuous fluid. We demonstrate an intra-droplet particle enrichment in a focused acoustic field.

Cited by 10 publications

References 30 publications

Light‐Fueled Submarine‐Like Droplet

Light‐Fueled Submarine‐Like Droplet

Micro-object manipulation by decanol liquid lenses

Concentration of Microparticles Using Flexural Acoustic Wave in Sessile Droplets

Contact Info

Product

Resources

About