Intra‐individual association between C‐reactive protein and insulin administration in postoperative lumbar spinal canal stenosis patients: A retrospective cohort study

Kurisu, Ken; Tsurutani, Yuya; Inoue, Kosuke; Hoshino, Yoshitomo; Saiki, Fumiko; Yoshiuchi, Kazuhiro

doi:10.1111/jdi.13210

Cited by 3 publications

(2 citation statements)

References 29 publications

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“…Multilevel modeling was used because this study used data with a hierarchical structure in which multiple records from each participant were analyzed [ 19 , 20 ]. Models were developed, including a null intercept model, and the fixed and random effects of level 1 and level 2 predictor variables were examined.…”

Section: Methodsmentioning

confidence: 99%

Association of psychosocial factors with physical activity among Japanese adults aged 65 and older: a 6-year repeated cross-sectional study from the Nakanojo Study

Dhakal,

Kurisu,

Park

et al. 2023

BioPsychoSocial Med

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Background Physical activity (PA) provides substantial mental and physical health benefits for individuals of all ages. A limited number of long-term or longitudinal studies have investigated the association between psychosocial factors and PA in healthy older adults aged 65 and above. This study aimed to determine the long-term relationship between psychosocial factors, such as vitality, mental health, anxiety, and depression, and objectively measure PA in older adults. Methods Healthy participants from Nakanojo, Japan, aged 65–90, capable of walking, were included in this study and were followed up from 2008 to 2013. Those diagnosed with dementia and depression were excluded. Using a repeated cross-sectional dataset, a multilevel model was developed with psychosocial variables as independent variables and an average daily duration of PA volume of > 3 metabolic equivalents (METs) as the outcome. The Akaike information criterion was used to select the final model. Results This study included 1108 records from 319 participants. In the multilevel model, age (coefficient = -0.106, 95% confidence interval [CI] = -0.127 to -0.086, p < 0.001) and the Hospital Anxiety and Depression Scale depression scores (coefficient = -0.019, 95% CI = -0.036 to -0.002, p = 0.026) were negatively associated with the duration of PA volume > 3 METs, whereas male sex (coefficient = 0.343, 95% CI = 0.115 to 0.571, p = 0.003) was positively associated with PA volume. Conclusion Depressive symptoms were related to a reduced duration of PA volume of > 3 METs among these adults aged 65 and above.

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Section: Methodsmentioning

confidence: 99%

Association of psychosocial factors with physical activity among Japanese adults aged 65 and older: a 6-year repeated cross-sectional study from the Nakanojo Study

Dhakal,

Kurisu,

Park

et al. 2023

BioPsychoSocial Med

Self Cite

View full text Add to dashboard Cite

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“…Eine japanische Arbeitsgruppe zeigte rezent, dass zwischen dem postoperativen Insulinbedarf nach Spinalkanalstenose-Operation bei Menschen mit DMT2 eine positive Korrelation mit dem Akut-Phase-Protein C-reaktives Protein (CRP) bestehen könnte. In der Modellberechnung stieg der Insulinbedarf um 0,60 Internationale Einheiten (IE) täglich pro CRP-Anstieg um 1 mg/dL [ 95 ]. Eine zunehmende Insulinresistenz durch Inflammation und postoperative Stresshormone machen dies aus pathophysiologischer Sicht erklärbar [ 94 , 96 ].…”

Section: Perioperative Stoffwechselkontrolle and Komplikationenunclassified

Position statement: surgery and diabetes mellitus (Update 2023)

Kietaibl

Huber²,

Clodi

et al. 2023

Wien Klin Wochenschr

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ZusammenfassungDas vorliegende Positionspapier beschreibt die Sicht der Österreichischen Diabetes Gesellschaft hinsichtlich des perioperativen Managements von Menschen mit Diabetes mellitus auf Basis der verfügbaren wissenschaftlichen Evidenz. Dabei wird Bezug genommen auf die präoperative Begutachtung und Vorbereitung sowie auf die perioperative Stoffwechselkontrolle mittels oraler Antidiabetika und/oder injektabler Therapie (Insulin‑/GLP-1-RA-therapie).

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The association between oral carbohydrate intake before orthopedic surgery for osteoporotic fractures and outcomes in elderly patients

Zhu,

Jin,

et al. 2023

J Orthop Surg Res

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Background Oral carbohydrate (CHO) intake is a safe method with effective clinical results in various surgical patients before surgery. Nevertheless, due to a lack of adequate clinical data, it is not frequently utilized in older patients undergoing orthopedic surgery for osteoporotic fractures (OPFs), especially in China. The purpose of the present study was to examine the relationship between preoperative oral CHO consumption and outcomes in elderly patients undergoing surgical treatment for OPFs. Methods This retrospective cohort study was conducted at a single Chinese institution and included a total of 879 elderly patients (median age: 71 years; range: 50–99 years) who underwent OPF surgery. Various exclusion criteria were established as follows: (a) the necessity for urgent surgical intervention; (b) the existence of hypoglycemia, hyperglycemia, or diabetes mellitus with blood glucose levels lower than 2.8 mmol/L; (c) a medical history of gastrointestinal motility disorders or delayed gastric emptying; (d) the utilization of local anesthesia; (e) a Charlson comorbidity index (CCI) score over 2; and (f) an American Society of Anesthesiologists (ASA) score exceeding 3. After propensity score (PS) matching, 264 patients from each cohort were included in the analysis. The primary outcome was the all-cause mortality rate within 60 days post-surgery, while secondary outcomes included the length of hospital stay (LOS), hospitalization costs, intraoperative and postoperative blood transfusions, and the incidence of postoperative nausea and vomiting (PONV) and aspiration. The relationship between preoperative oral CHO intake and outcomes was evaluated using multivariate regression analysis. Results After PS matching, preoperative oral CHO intake was negatively associated with 60-day mortality in the fully adjusted model (odds ratio 0.35; 95% confidence interval 0.12–0.97; P-value: 0.04). Patients who received preoperative oral CHO intake also had a shorter LOS and lower hospitalization costs than those who did not receive CHO intake. However, none of the models showed a significant association between CHO intake and PONV or blood transfusion risk. Furthermore, no cases of aspiration were observed in either cohort. Conclusions Preoperative oral CHO intake may be associated with reduced mortality risk and improved outcomes in elderly patients undergoing surgical treatment for OPFs. However, it is important to acknowledge the limitations of our study, including its retrospective nature, potential unmeasured confounding variables, the small sample size, incomplete data on important variables such as duration of surgery and inflammatory markers, and the limited generalizability due to the participation of only one institution. Future research with larger sample sizes and a broader range of events is warranted to validate and enhance the validity of our findings, particularly in assessing long-term results and understanding the underlying mechanisms.

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Intra‐individual association between C‐reactive protein and insulin administration in postoperative lumbar spinal canal stenosis patients: A retrospective cohort study

Cited by 3 publications

References 29 publications

Association of psychosocial factors with physical activity among Japanese adults aged 65 and older: a 6-year repeated cross-sectional study from the Nakanojo Study

Association of psychosocial factors with physical activity among Japanese adults aged 65 and older: a 6-year repeated cross-sectional study from the Nakanojo Study

Position statement: surgery and diabetes mellitus (Update 2023)

The association between oral carbohydrate intake before orthopedic surgery for osteoporotic fractures and outcomes in elderly patients

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