2016
DOI: 10.1186/s12890-016-0258-5
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Intra-patient comparison of parietal pleural biopsies by rigid forceps, flexible forceps and cryoprobe obtained during medical thoracoscopy: a prospective series of 80 cases with pleural effusion

Abstract: BackgroundThere is only few data available on the use of cryotechnique during medical thoracoscopy.MethodsMedical thoracoscopy was performed in consecutive patients with pleural effusion. Prospectively, biopsies were taken by rigid forceps, flexible forceps and cryoprobe. Specimen size, depth and diagnostic yield were compared.Results80 Patients were included. 408 biopsies were taken (205 rigid biopsies, 104 flexible biopsies, 99 cryobiopsies). Mean surface area of rigid biopsies was 22.6 ± 20.4 mm2 (flexible … Show more

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Cited by 29 publications
(15 citation statements)
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“…A total of seven observational studies representing 586 biopsies (311 cryobiopsies and 275 flexible forceps biopsies) were analyzed. [9][10][11][12][13][14][15] Our assessment of study quality is available in e-Appendix 1. In most instances, the risk of bias was assessed to be low or unclear.…”
Section: Resultsmentioning
confidence: 99%
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“…A total of seven observational studies representing 586 biopsies (311 cryobiopsies and 275 flexible forceps biopsies) were analyzed. [9][10][11][12][13][14][15] Our assessment of study quality is available in e-Appendix 1. In most instances, the risk of bias was assessed to be low or unclear.…”
Section: Resultsmentioning
confidence: 99%
“…All studies used both cryobiopsies and flexible forceps biopsies, whereas all but one study used a semi-rigid thoracoscope. Wurps et al 12 used a rigid thoracoscope instead, and sequentially used rigid forceps (four samples), flexible forceps (one to two samples), and the cryoprobe (one to two samples); only the latter two techniques were included in our analysis for purposes of consistency. In all studies except one, both cryobiopsy and flexible biopsy were performed on the same patient; in Tousheed et al, 14 the first 52 consecutive patients underwent only flexible forceps biopsy because of unavailability of cryobiopsy equipment and the final 87 consecutive patients underwent only cryobiopsy with no change in the procedural indication.…”
Section: Resultsmentioning
confidence: 99%
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“…They proposed the possible use of pleural cryobiopsies when rigid biopsies were not available. 24 In another prospective observational single-center study, Chen et al prospectively enrolled 92 patients with exudative effusions who underwent thoracentesis and closed pleural biopsy (CPB) followed by flexi-rigid thoracoscopy with flexible forceps and the cryoprobe. The diagnostic yield for each technique was: cell block 32/92 (34.8%); CPB 25/92 (27.5%), flexible forceps 84/92 (91.3%), and the cryoprobe 91/92 (98.9%).…”
Section: Advances and Controversies In Medical Thoracoscopymentioning
confidence: 99%