Intra-uterine insemination for male subfertility

Bensdorp, A; Cohlen, BJ; Heineman, MJ; Vandekerckhove, P

doi:10.1002/14651858.cd006328

Cited by 28 publications

(30 citation statements)

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“…It is the usual control treatment in trials of IUI (20). There were no differences between pregnancy rates per couple for IUI vs. TI in stimulated cycles in male infertility (OR 1.67, 95% CI 0.83–3.37) (14). In a randomized trial, Agarwal and Mittal (21) compared IUI and TI in superovulated cycles with CC in 140 couples with unexplained infertility.…”

Section: Introductionmentioning

confidence: 96%

“…Currently, intrauterine insemination (IUI) with or without ovarian stimulation is widely used to treat male infertility and unexplained infertility, and for couples with minimal and mild endometriosis (13–17). The rationale of IUI treatment is to increase the rate of conception in the couple by increasing the chance that the maximum number of healthy sperm will reach the site of fertilization.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Expression of Concern: Intrauterine insemination versus timed intercourse with clomiphene citrate in polycystic ovary syndrome: a randomized controlled trial

Hashim¹,

Ombar²,

Elaal

2011

Acta Obstet Gynecol Scand

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Section: Introductionmentioning

confidence: 96%

Section: Introductionmentioning

confidence: 99%

Expression of Concern: Intrauterine insemination versus timed intercourse with clomiphene citrate in polycystic ovary syndrome: a randomized controlled trial

Hashim¹,

Ombar²,

Elaal

2011

Acta Obstet Gynecol Scand

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show abstract

“…Intrauterine insemination (IUI) is a common treatment modality for couples with moderate male factor infertility (Comhaire et al ., ; Ombelet et al ., ) although evidence of its effectiveness is inconclusive (Bendsdrop et al ., ). It is usually recommended that the male refrain from ejaculation for 2–5 days prior to treatment in order to improve sperm quality.…”

Section: Introductionmentioning

confidence: 97%

Twenty-four hours abstinence and the quality of sperm parameters

et al. 2013

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Patients with abnormal basic parameters and mainly low concentration can be expected to have improved parameters on the second consecutive day. As the number of abnormal basic parameters increases, the more significant improvement can be expected. On the other hand, patients with normal or few abnormal basic semen parameters show a decrease after 24 h. Furthermore, the magnitude of change to both directions in TMC and TNMC values in these patients emphasises these conclusions. Based on the type and mainly the combined number of abnormal basic semen parameters, insemination strategy can be tailored to male fertility patients. Those with abnormal concentration or multiple abnormal semen parameters may benefit from 2 consecutive day intercourses or inseminations or a short period of abstinence due to a significant improvement in the semen parameters on second day insemination. In those with normal basic semen parameters, a reduction in semen quality is expected after 24 h, and a single-timed insemination and longer abstinence can be recommended.

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“…Intrauterine insemination (IUI) is a noninvasive therapy which can be carried out with the husband's semen (AIH) or with donor semen (AID). AID is regarded as a first‐line treatment option for couples with severe male‐factor infertility (Duran et al ., ; Zhao et al ., ; Bensdorp et al ., ), even though the assisted reproductive technologies (ARTs) such as in vitro fertilisation (IVF) and intracytoplasmic sperm injection (ICSI) have been well developed. AID can be a successful alternative because of its simplicity, easy management, low cost and absence of potentially serious complications (Ok et al ., ).…”

Section: Introductionmentioning

confidence: 99%

Relationship between donor sperm parameters and pregnancy outcome after intrauterine insemination: analysis of 2821 cycles in 1355 couples

et al. 2015

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The aim of this study was to investigate whether sperm parameters can affect the pregnancy outcome of artificial intrauterine insemination with cryopreserved donor spermatozoon (AID). A total of 1355 couples received 2821 AID treatment cycles in the Reproductive Medicine Center of the Tongji Medical College between January 2010 and December 2013, and the data were collected and retrospectively analysed. The relationship between pre-freezing, post-thawing as well as optimised sperm parameters and AID pregnancy outcome was investigated. Clinical pregnancy rate and cumulated pregnancy rate were also calculated. A total of 728 cycles from 2821 treatment cycles achieved pregnancies, and cumulated pregnancy rate was 25.81%. Pre-freezing progressive sperm motility in pregnant cycles was higher than that in nonpregnant cycles (P = 0.001); logistic regression analysis also indicated that pre-freezing progressive sperm motility was the only parameter affecting pregnancy outcome (P = 0.0001). Our study also showed that the cumulated pregnancy rate increased progressively and reached a plateau after the fifth cycle. In conclusion, pre-freezing progressive sperm motility should be a valuable predictor for AID pregnancy outcome. Female fertility factors should be considered, or IVF/ICSI should be recommended when couples received more than 5 AID cycles without pregnancy.

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Intra-uterine insemination for male subfertility

Cited by 28 publications

References 0 publications

Expression of Concern: Intrauterine insemination versus timed intercourse with clomiphene citrate in polycystic ovary syndrome: a randomized controlled trial

Expression of Concern: Intrauterine insemination versus timed intercourse with clomiphene citrate in polycystic ovary syndrome: a randomized controlled trial

Twenty-four hours abstinence and the quality of sperm parameters

Relationship between donor sperm parameters and pregnancy outcome after intrauterine insemination: analysis of 2821 cycles in 1355 couples

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