Intraarticular levobupivacaine or bupivacaine administration decreases pain scores and provides a better recovery after total knee arthroplasty

Abstract

Intraarticular bupivacaine and levobupivacaine provided better postoperative analgesia both at rest and during mobilization in total knee replacement surgery compared to control. Tramadol consumption and hospital stay were also decreased in the study groups.

Intra Articular Administration; To Determine the Analgesic Efficacy of Bupivacaine and Compare It With Levobupivacaine, During Surgical Procedures of the Knee Joint

“…According to the results of our study the VAS scores were found to be lower in the bupivacaine group in the initial few hours postoperatively (4,8,12,24 hours), but they were lower for the levobupivacaine group at the 48 th hour, virtually everything else such as the requirement for PCEA (boluses and dosage), physiotherapy associated pain, discharge and mobilization times were identical. We had utilized in our study intra articular injections of the two drugs, paracetamol and PCEA as modalities to relieve the postoperative pain.…”

“…All the patients were monitored intra operatively using standardized equipment. Readings of echocardiograph, blood pressure and pulse oximetry at regular time intervals (at 5,15,30,60 and 90 mins or till end of procedure) as well as sensory and motor characteristics of the established block at various intervals (2,4,8,12,24,48 and 72 hours postoperatively) side effects, number of boluses and doses of PCEA, total amount of pain relief medications utilized over the period was observed, VAS scores and time of mobilization and discharge from the hospital were also noted in a pre-designed proforma.…”

“…In comparison with bupivacaine, levobupivacaine has more margin of safety in terms of side effects when used in big doses. 4 Intravenous analgesics fail is to provide analgesia at rest, relief from motion related pain and the spasms of the musculature, hence intra articular drugs are preferred. 5 The aim of our study is to provide a comparison between levobupivacaine and bupivacaine administered intra articulary in the knee joint during arthroplasty procedures, and compare the postoperative analgesic effect using the VAS score.…”

Knee Arthroplasty Surgery: Comparison of Intra-Articular Levobupivacaine and Dexmedetomidine with Ropivacaine and Dexmedetomidine for Post Operative Pain Management

“…[11] Kazak Bengisun et al found that use of levobupivacaine and bupivacaine intra-articularly produced lesser rescue analgesic consumption and lower VAS score which was similar to our study. [12] Paul et al concluded that intra-articular dexmedetomidine added as an adjunct to ropivacaine in patients undergoing arthroscopic knee surgery improved the quality and duration of postoperative analgesia. [13] Das et al in their study compared intraarticular ropivacaine ,fentanyl and dexmedetomidine for pain relief and suggested that ropivacaine was better than both fentanyl and dexmedetomidine.…”

Erratum zu: Infektionsprävention durch das Anästhesieteam

“…We are fully aware of and share Dr Zink's concerns about the chondrotoxic effects of local anesthetics. Dr Zink pointed out that "there is good evidence that intra-articular injection of local anesthetics may result in severe damage in cartilage tissue"; however, as far as we know there are no data about the chondrotoxic effect of levobupivacaine while anesthesiologists are using it widely in the clinic even intra-articularly [1,2]. For these reasons we designed this study.…”