Intracanal irrigants for pulpectomy in primary teeth: a systematic review and meta‐analysis

Pozos‐Guillén, Amaury; Garcia-Flores, Adrian; Esparza-Villalpando, Vicente; Garrocho‐Rangel, Arturo

doi:10.1111/ipd.12228

Cited by 37 publications

(32 citation statements)

References 34 publications

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“…Pulpectomy is an endodontic technique recommended for the treatment of irreversible pulp inflammation or necrosis caused by dental trauma or caries and is considered a conservative option compared with tooth extraction. 4,5 The main goal of this endodontic intervention is to recover the function of the affected tooth by treating or preserving the integrity of the periapical tissue and to prevent subsequent reinfection by eliminating microorganisms from root canals. 6 Although most randomised clinical trials have reported satisfactory success rates for primary tooth pulpectomy, [7][8][9] these studies included procedures performed without sedation or general anaesthesia.…”

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confidence: 99%

Analysis of survival and factors associated with failure of primary tooth pulpectomies performed under general anaesthesia in children from South China

Chen

et al. 2019

Int J Paed Dentistry

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Background Pulpectomy is a technique recommended for treatment of irreversible pulp inflammation or necrosis. Treatment‐related variables and patient factors may affect the prognosis of pulpectomy. Aim To investigate the survival and related predictors associated with failure of pulpectomies performed under general anaesthesia for early childhood caries. Design Dental records of 124 patients, who underwent pulpectomy as part of comprehensive dental treatment under general anaesthesia, were reviewed and assessed. Relapse of pulpitis and periodontal periodontitis were evaluated by clinical examination and periapical film assessment at each follow‐up appointment after original treatment. Results A total of 389 teeth of 124 children were evaluated. By the end of the fourth year, 45% of teeth with pulpitis and 46% of teeth with periapical periodontitis were estimated to relapse; the median (interquartile range) number of years to relapse was 3.5 (3.4‐3.8) and 3.0 (1.8‐3.0) years, respectively. The follow‐up frequency, number of teeth extracted, plaque index, tooth position, type of restoration, pulp status, and quality of root canal filling were observed to have independent effects on relapse. Conclusion Recurrence came earlier in teeth diagnosed with periapical periodontitis than those with pulpitis. Both treatment‐related variables and patient factors could affect the prognosis of pulpectomy.

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confidence: 99%

Analysis of survival and factors associated with failure of primary tooth pulpectomies performed under general anaesthesia in children from South China

Chen

et al. 2019

Int J Paed Dentistry

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“…Full text retrieval was limited to 52 publications out of which 28 (Appendix ) were excluded due to absence of MA. Final selection identified 24 SRs with MA . The characteristics of the SRs with MA are presented in Table .…”

Section: Resultsmentioning

confidence: 99%

“…Among the study topics in Paediatric Dentistry, most of the SRs focused on preventive strategies (37.5%) followed by restorative procedures (16.6%), pediatric endodontic procedures (16.6%), and behavior management aspects (16.6%). On contacting the authors on the scores, eight out of 24 authors responded . Three authors agreed to the scores and five authors provided justification for changes in the scores.…”

Section: Resultsmentioning

confidence: 99%

Critical appraisal of methodological quality of Systematic Reviews and Meta‐analysis in Paediatric Dentistry journals

Jayaraman

Nagendrababu

Pulikkotil

et al. 2018

Int J Paed Dentistry

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“…The methodological quality and validity of the included studies were independently assessed by two blinded reviewers using Grading of Recommendations Assessment, Development and Evaluation (GRADE) (Atkins et al, ) and Oxford Centre for Evidence‐Based Medicine (OCEMB) (Howick et al, ) criteria, employing the table reported by Pozos‐Guillen, Garcia‐Flores, Esparza‐Villalpando, and Garrocho‐Rangel (), both considered suitable for reducing potential biases in terms of quality of RCTs (Pozos‐Guillen et al, ; Urrútia & Bonfill, ). The reviewers scored each scale section based on their judgment and knowledge, in order to determine the weight of the respective section in terms of the final results and conclusions of each individual study.…”

Section: Methodsmentioning

confidence: 99%

Analgesic efficacy of preoperative dexketoprofen trometamol: A systematic review and meta‐analysis

Esparza-Villalpando

Pozos‐Guillén

Masuoka

et al. 2017

Drug Development Research

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Post-Market Research Clinical evidence supports the use of dexketoprofen trometamol (DEX) to manage acute postoperative pain. However, controversies surround the impact of the use of this drug in preoperative analgesic protocols. The aim of the present meta-analysis was to evaluate the effectiveness of the preoperative administration of DEX under postoperative pain conditions. Electronic and manual searches were conducted through diverse electronic databases. A systematic review and meta-analysis to evaluate the analgesic efficacy of the preoperative administration of DEX was performed including Randomized Clinical Trials (RCTs) published between 2002 and 2017. Suitable individual studies were evaluated through a quality system, and the data were extracted and analyzed. Fourteen RTCs were included (12 parallel trials and 2 cross-over trials), published in the English and Turkish languages. Follow-up periods ranged from 4, 6, 8, 24, and 48 hr. All trials measured the outcome result as Acute Pain Level (APL) (VAS, NRS, VRS), time to requiring a second dose of DEX or analgesic emergency and consumption of opioids via patient-controlled analgesia. When the comparators were other drugs - paracetamol, Lornoxicam or placebo during the preoperative time, preoperative administration of DEX was superior. When the comparison comprised preoperative and postoperative DEX, both alternatives exhibited comparable analgesic effects. The analgesic efficacy of the preoperative administration of DEX when compared to placebo, lornoxicam, and paracetamol on postoperative pain was evident. Preoperative administration of DEX compared to its immediate postoperative administration showed a similar analgesic effect.

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Intracanal irrigants for pulpectomy in primary teeth: a systematic review and meta‐analysis

Abstract: More studies are required with adequate quality, as well as a full-result report, including summary measurements of both response variables and effect size, to determine the most effective irrigant agents for use in pulpectomies.

Cited by 37 publications

References 34 publications

Analysis of survival and factors associated with failure of primary tooth pulpectomies performed under general anaesthesia in children from South China

Analysis of survival and factors associated with failure of primary tooth pulpectomies performed under general anaesthesia in children from South China

Critical appraisal of methodological quality of Systematic Reviews and Meta‐analysis in Paediatric Dentistry journals

Analgesic efficacy of preoperative dexketoprofen trometamol: A systematic review and meta‐analysis

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