SummaryThe stretched size of an atrial septal defect (ASD) is important for device selection during transcatheter closure. However, balloon sizing carries potential risks such as hypotension, bradycardia, or laceration of the atrial septum. The aim of the present study was to investigate the accuracy of the predicted stretched size of ASD by intracardiac echocardiography (ICE).From December 2004 to November 2007, 136 consecutive patients with single secundum type ASD undergoing transcatheter closure of their defect using the Amplatzer septal occluder under ICE guidance were enrolled for analysis.There were 43 males and 93 females. The age ranged from 2.2 to 79.1 years with a median age of 13.4 years. The body weight ranged from 12.1 to 93.2 kg with a median body weight of 45.8 kg. The stretched size of ASD measured by a sizing plate was considered as the standard. ASD sizes measured by ICE in bicaval and short-axis views predicted the stretched size by formulae derived from linear regressions. The predicted stretched sizes obtained using 2 formulae, 1.34 × bicaval × short axis √ (formula 1) and 1.22 x larger diameter (formula 2), exhibited good agreement with the standard stretched size with Kappa values of 0.91 and 0.90, respectively. The accuracy rate of predicted stretched sizes within 2 mm, 3 mm, and 4 mm range of the standard size were 32.8%, 45.4%, and 57.7% (formula 1) and 33.1%, 50%, and 63.2% (formula 2).The stretched size of ASD predicted by ICE exhibited good agreement with the standard stretched size. This prediction provides helpful information, especially if balloon sizing cannot be adequately performed. (Int Heart J 2010; 51: 56-59) Key words: Atrial septal defect, Heart catheterization, Intracardiac echocardiography, Transcatheter closure T ranscatheter closure of a secundum type atrial septal defect (ASD) using the Amplatzer Septal Occluder (ASO, AGA Medical, Golden Valley, MN) is a standard procedure nowadays.1-3) During the procedure, an accurate determination of the defect size is crucial for successful device deployment. The stretched size of ASD measured by balloon sizing is the standard method for device selection. However, it carries potential risks of hypotension, bradycardia, or laceration of the atrial septum. 4,5) Furthermore, it is difficult to perform if the ASD is large. In this situation, prediction of the stretched size of ASD without balloon sizing becomes critical.Traditionally, transesophageal echocardiography (TEE) was used for assessing ASD size, device position, and possible residual shunts.2,3) However, TEE has certain drawbacks such as needing general anesthesia and possible esophageal trauma. Through more than a decade of development, intracardiac echocardiography (ICE) is proved to be safe, effective, and user-friendly to guide transcatheter closure of ASD without the need for general anesthesia. [6][7][8][9][10] The aim of this study was to investigate the accuracy of the predicted stretched size of ASD by ICE.
MethodsFrom December 2004 to November 2007, 136 consecutiv...