Intracardiac electrography in patients before and after surgical repair of secundum atrial septal defect

Long-term Noninvasive Arrhythmia Assessment after Surgical Repair of Sinus Venosus Atrial Septal Defect

“…Further evidence supporting the notion that there may be an intrinsic abnormality of the sinus node and atrial conduction tissue in patients with ASDs comes from studies demonstrating a high prevalence of preoperative SND, 31,32 a finding that did not correct at postoperative follow-up. [33][34][35] Another proposed theory is that preoperative SND is a result of atrial stretch from prolonged right atrial volume overload 36 as SND was not seen preoperatively in a subset of subjects under age 2.5 years. 37 Further investigation, with appropriate control groups, is necessary to distinguish between these possible etiologies.…”

“…Alternatively, SND may be an intrinsic abnormality that is recognized late in patients with SVASD because patients with an IVC‐type defect also developed SND after a surgical procedure performed distant from the normal location of the sinus node and sinus node artery. Further evidence supporting the notion that there may be an intrinsic abnormality of the sinus node and atrial conduction tissue in patients with ASDs comes from studies demonstrating a high prevalence of preoperative SND, 31,32 a finding that did not correct at postoperative follow‐up 33–35 . Another proposed theory is that preoperative SND is a result of atrial stretch from prolonged right atrial volume overload 36 as SND was not seen preoperatively in a subset of subjects under age 2.5 years 37 .…”

Persistent electrical and morphological atrial abnormalities after early closure of atrial septal defect

“…Electrophysiological abnormalities, such as prolonged sinu-atrial conduction, and increased atrial functional refractory periods, have been reported in pre-operatively in patients with an atrial septal defect. 9,10 In adults, pre-operative atrial fibrillation tends to have persisted after closure, albeit that other atrial tachyarrhythmias may resolve. A higher incidence of arrhythmias has also been reported in children after closure.…”