Intracardiac metastasis from known cervical cancer: a case report and literature review

Byun, Seung Won; Park, Sung Taek; Ki, Eun Young; Song, Hyun; Hong, Seung Wook; Park, Jong Sup

doi:10.1186/1477-7819-11-107

Cited by 26 publications

(39 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Мета-стазы в сердце следует подозревать у пациентов с онкологическим анамнезом при развитии при-знаков сердечной недостаточности либо ТЭЛА, особенно когда источник эмболии не может быть четко идентифицирован [5].…”

Section: Discussionunclassified

“…Средняя продолжительность жизни пациентов с таким диагнозом, по данным различ-ных авторов, не превышает 6 мес [5]. Оперативное вмешательство по поводу опухолей сердца сопро-вождается высоким риском периоперационной ле-тальности и требует взвешенного решения [6,7].…”

Section: Discussionunclassified

See 1 more Smart Citation

Surgical Correction of Cardiac Metastases From Cervical Cancer

et al. 2018

View full text Add to dashboard Cite

Metastases to the heart are extremely rare, and the reported incidence of cardiac metastasis at autopsy ranges from 1.5 to 21.8 %. In cancer patients, cardiac metastases are usually difficult to diagnose unless the patients do not complain of any related symptoms. Common tumors with cardiac metastasis potential are usually carcinomas of the lung, breast, and malignant lymphoma. The prognosis of a metastatic heart tumor is unfavorable. The average life expectancy for patients with this diagnosis is less than six months. In addition, surgical treatment of primary cardiac tumors or metastatic cardiac tumors is associated with high risk of perioperative lethality. Case report. We present a rare case of cervical cancer metastasis to the heart in a 33-year-old woman. Cytological examination revealed no evidence of disease recurrence 14 months after the completion of external beam radiotherapy. Echocardiography showed a mass in the outflow tract of the right ventricle and findings of severe pulmonary hypertension. omputed tomography and magnetic resonance imaging revealed a large right ventricular thrombus. The patient underwent surgery with artificial circulation. Pathohistological and immunohistochemical studies revealed metastasis of squamous cell carcinoma. The control echocardiography showed decrease in pulmonary hypertension. No evidence of right ventricular mass was detected. Conclusion. Cardiac metastasis should be included in the differential diagnosis in patients with complaints of dyspnea and chest pain, especially in cases with history of cancer. Surgical treatment of cardiac metastasis contributes to the prevention of cardiopulmonary complications and improvement of survival rates in this group of patients.

show abstract

Section: Discussionunclassified

Surgical Correction of Cardiac Metastases From Cervical Cancer

et al. 2018

View full text Add to dashboard Cite

show abstract

“…Furthermore, the genetic basis for cardiac involvement of cervical cancer has not been clearly established 17. Treatment options are generally considered palliative, and surgical excision has only been offered in cases of isolated right ventricular involvement, and otherwise limited metastatic burden and excellent functional status 7…”

Section: Discussionmentioning

confidence: 99%

Biventricular metastatic invasion from cervical squamous cell carcinoma

Kapoor¹,

Evans

Shkullaku

et al. 2016

BMJ Case Reports

View full text Add to dashboard Cite

show abstract

“…In the present case, tumor embolism was not directly diagnosed by imaging but was highly suspected based on indirect findings such as acute onset type I respiratory failure, dilatation of peripheral pulmonary arteries, mosaic ground-grass opacities in chest CT images, significant pulmonary hypertension, presence of a mass in the right ventricle, and elevated right ventricular pressure. Pulmonary tumor embolism in cervical cancer has been reported mostly in patients with cardiac metastasis (Table II) (7)(8)(9)(10)(11)(12)(13)(14)(15), suggesting that pulmonary tumor embolism should be considered in the differential diagnosis of patients with findings that suggest cardiac metastasis, even in the absence of typical imaging findings (e.g., perfusion defects in major pulmonary arteries).…”

Section: Discussionmentioning

confidence: 99%

Pulmonary Tumor Embolism Due to Squamous Cell Carcinoma of the Uterine Cervix: A Case Report

Okazaki

Abe

Takayanagi

et al. 2018

View full text Add to dashboard Cite

Abstract. Background Pulmonary tumor embolism is a rare and fatal complication in cancer patients. It leads to progressive clinical manifestations including respiratory failure, pulmonary hypertension, right heart failure, and sudden death (1). Generally, tumor embolism is more common in patients with adenocarcinoma compared to other histological types (2). This report describes a case in which a patient with squamous cell carcinoma of the uterine cervix developed pulmonary tumor embolism and followed a fatal clinical course within a few days after the onset of symptoms, along with multimodal diagnostic imaging and autopsy findings. Case PresentationClinical findings. A 60-year-old female visited a local clinic with a chief complaint of continuous genital bleeding. She was referred to our institution with suspected cervical cancer. Pelvic examination revealed an easily bleeding mass occupying the external uterine orifice, with bilateral parametrial and lower vaginal infiltration. Magnetic resonance imaging (MRI) revealed a large tumor in the uterine cervix that had invaded into the uterine corpus, bilateral parametria, vagina, rectum, and bladder (Figure 1). MRI also showed multiple enlarged pelvic lymph nodes. Computed tomography (CT) revealed multiple low-density lesions in the liver, suggesting liver metastases. A biopsy of the cervical mass revealed a keratinizing squamous cell carcinoma of the uterine cervix, and the patient was diagnosed with stage IVB (cT4N1M1) cervical cancer. One week later, she developed progressive dyspnea, cyanosis, tachycardia (105 beats per minute), and tachypnea (30 breaths per minute). Her peripheral capillary oxygen saturation was 80-85%, and her blood pressure and body temperature were normal. No abnormal findings were noted on auscultation of both lungs. Arterial blood gas analysis showed alkalemia (pH 7.482), decreased levels of arterial oxygen tension (PaO 2 , 54.9 mmHg), arterial carbon 337

show abstract

Intracardiac metastasis from known cervical cancer: a case report and literature review

Cited by 26 publications

References 11 publications

Surgical Correction of Cardiac Metastases From Cervical Cancer

Surgical Correction of Cardiac Metastases From Cervical Cancer

Biventricular metastatic invasion from cervical squamous cell carcinoma

Pulmonary Tumor Embolism Due to Squamous Cell Carcinoma of the Uterine Cervix: A Case Report

Contact Info

Product

Resources

About