Intracardiac Thrombosis and Embolism in Endomyocardial Fibrosis in Uganda

Embolic Complications of Cardiomyopathy

“…Intracardiac thrombosis and embolism are also features of the endomyocardial fibrosis of East Africa. Shaper and Wright (1963) have analysed its occurrence in necropsy material and compared this with its incidence in the South African cardiomyopathy. It appears that both thrombosis and embolism are more frequent in the latter condition, and the clinical occurrence of embolic phenomena in endomyocardial fibrosis is rare.…”

Eosinophilia and heart disease.

“…A further point in favour of the unitarian view is the high incidence of intracardiac thrombosis and embolism both in Loffler's disease with eosinophilia and in the disease which Becker described without eosinophilia. While embolism does occur in endomyocardial fibrosis (Shaper and Wright, 1963;Owor, 1973) it is fairly rare perhaps because the earlier stages of the disease are not recognised (Patel et al, 1977). The apparent difference may be related to the lesser aggressiveness and greater chronicity of the process at the stage of endomyocardial fibrosis.…”

Endomiocardiofibrose como Causa Rara de Transplante Cardíaco e Associação com Trombofilia: Relato de Caso

“…No presente caso, a associação entre a EMF e a trombofilia levantou a hipótese de que a EMF pudesse ser uma consequência da organização de eventos sucessivos de trombose intracardíaca que levam a fibrose e contração das trabéculas ventriculares. Na verdade, já se propôs que um estado pró-trombótico tenha um papel na patogênese da EMF 5,6 Shaper e…”