Intracavitary cardiac metastasis and pulmonary tumor emboli of choriocarcinoma: The first case diagnosed and treated without surgical intervention

Bozacı, Elif Aylin; Taşkın, Salih; Gürkan, Özlem Ural; Atasoy, Çetin; Ersoy, Zinet Gül; Erekul, Selim; Numanoğlu, Numan; Ortaç, Fırat

doi:10.1016/j.ygyno.2005.07.012

Cited by 13 publications

(15 citation statements)

References 10 publications

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“…Clinical features including rapid onset of symptoms with PH and acute right heart failure would be indistinguishable. Tumour macroembolism is reported in cases of breast cancer [59], hepatocellular carcinoma [60], choriocarcinoma [10,55,61,62] and, less often, subdiaphragmatic cancers including cervical carcinoma [63]. PTE/PTTM may of course coexist [4,60].…”

Section: Tumour Macroembolismmentioning

confidence: 99%

Tumoral pulmonary hypertension

et al. 2019

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Tumoral pulmonary hypertension (PH) comprises a variety of subtypes in patients with a current or previous malignancy. Tumoral PH principally includes the tumour-related pulmonary microvascular conditions pulmonary tumour microembolism and pulmonary tumour thrombotic microangiopathy. These inter-related conditions are frequently found inpost mortemspecimens but are notoriously difficult to diagnoseante mortem. The outlook for patients remains extremely poor although there is some emerging evidence that pulmonary vasodilators and anti-inflammatory approaches may improve survival. Tumoral PH also includes pulmonary macroembolism and tumours that involve the proximal pulmonary vasculature, such as angiosarcoma; both may mimic pulmonary embolism and chronic thromboembolic PH. Finally, tumoral PH may develop in response to treatments of an underlying malignancy. There is increasing interest in pulmonary arterial hypertension induced by tyrosine kinase inhibitors, such as dasatanib. In addition, radiotherapy and chemotherapeutic agents such as mitomycin-C can cause pulmonary veno-occlusive disease. Tumoral PH should be considered in any patient presenting with unexplained PH, especially if it is poorly responsive to standard approaches or there is a history of malignancy. This article will describe subtypes of tumoral PH, their pathophysiology, investigation and management options in turn.

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Section: Tumour Macroembolismmentioning

confidence: 99%

Tumoral pulmonary hypertension

et al. 2019

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“…However, metastatic disease to the heart in such a case is exceedingly rare, with only a few reported cases. 7 The prevalence of right atrial thrombus varies according to the clinical scenario, affecting less than 1% of patients with atrial fibrillation 4 and 5% of those undergoing chemotherapy with a central venous catheter. 5 Right atrial thrombi have been classified into three main types.…”

Section: Discussionmentioning

confidence: 99%

Right atrial mass in a 23-year-old woman with molar pregnancy

Sharma

Sidhu

Paterson

2015

CMAJ

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“…Dans cette observation les localisations rénale et pulmonaire se sont manifestées cliniquement de façon brutale. Des cas d'hémoptysie, de dyspnée ou moins fréquemment d'hématurie mettant en jeu le pronostic vital ont été rapportés [6].…”

Section: Discussionunclassified

“…Les tumeurs primitives sont le plus souvent des carcinomes bronchiques mammaires ou coliques, des mélanomes, voire des sarcomes [6,12]. Par ailleurs, les métastases pulmonaires de choriocarcinomes sont classiquement représentées par une dizaine de nodules parenchymateux de 1 à 3 cm, plus rarement par une pleurésie ou une masse parenchymateuse unique [6]. Afin de pallier ces difficultés diagnostiques, la FIGO a défini en 2000 des critères diagnostiques de MTG.…”

Section: Discussionunclassified