Intracranial Ameloblastoma Arising from the Maxilla: An Interdisciplinary Surgical Approach

Quick-Weller, Johanna; Koch, Felix P.; Dinc, Nazife; Lescher, Stephanie; Baumgarten, Peter; Harter, Patrick N.; Scheerer, Friedrich; Sader, Robert; Seifert, Volker; Marquardt, Gerhard; Freiman, Thomas M.

doi:10.1055/s-0036-1594236

Cited by 6 publications

(4 citation statements)

References 23 publications

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“…Thus, invasion of the temporal bone by ameloblastoma is favoured over a true brain metastasis. Case of a 57-year-old patient who was admitted with a huge tumour involved the nasal cavity, the left maxilla, and the anterior fossa [13] which also presented with eye involvement consistent with our case. Tong et al [14] presented a case of ameloblastoma reoccurred in the soft tissues after repeated curettage, This case illustrated that it is possible to treat ameloblastoma in accessible regions of the mandible by repeated curettage, thus sparing the patient morbidity of more ablative surgery for many years.…”

Section: Literature Review and Discussionsupporting

confidence: 84%

A Case Report with Literature Review: Recurrence of Peripheral Ameloblastoma with Intracranial Extension

Mahjoub

2020

ADOH

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Introduction: Ameloblastoma is generally considered to be a benign lesion with locally invasive behavior and a tendency to reoccur after inadequate treatment. The risk of recurrence is reported to be significantly reduced by radical treatment compared with conservative surgical treatment.Case Report: A 37 year's old male patient presented to Khartoum Dental Teaching hospital in July 2020 with painful firm pink fleshy mass with areas of necrosis in the parotid region that bleeds continuously and associated with sense of relief after bleeding, it started as small lesion that progressed in 10 months duration. The left eye underwent exophthalmos, hazy vision, severe pain and continuous tearing. The patient is operated two times in the last 15 years. Conclusion:Peripheral Ameloblastoma can have an aggressive invasive behavior resembling malignancy. High rate intracranial extension can occur in short period making surgical intervention for complete removal of the lesion difficult and only confined to surgical debulking to improve quality of life. Close long term follows up of Ameloblastoma after primary treatment is mandatory.

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Section: Literature Review and Discussionsupporting

confidence: 84%

A Case Report with Literature Review: Recurrence of Peripheral Ameloblastoma with Intracranial Extension

Mahjoub

2020

ADOH

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“…However, OLAITAN[ 15 ] in a series of 315 Nigerian patients reported male dominance (61.9%) and common presentation between 30 and 40 years. [ 15 , 17 ]…”

Section: Discussionmentioning

confidence: 99%

“…The treatment of these lesions is associated to multiple surgeries and radiation therapy witch is indicated when a subtotal resection of tumor occurs. [ 17 , 20 ] The duration of disease and increased number of recurrences appear to be risk factors for intracranial involvement. [ 20 ]…”

Section: Discussionmentioning

confidence: 99%

“…Low recurrence rates were reported by the authors when a total resection surgery occurs (total tumor resection includes the dental and alveolar structures). [ 17 ] A long-time survival was reported in 81.8% of cases in a Nigerian study associated with radical surgery (follow-up ranged 6 months to 13 years). In this study, all the cases were originated in the mandible.…”

Section: Discussionmentioning

confidence: 99%

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Pure endoscopic transsphenoidal treatment of skull base ameloblastoma with intracranial extension: Case report and literature review

Ferreira

Pimentel

Albuquerque

et al. 2020

Surgical Neurology International

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Background: Ameloblastoma is a benign locally invasive lesion that represents 1% of all oral tumors. Epidemiological characteristics are variable in the literature. The most common origin sites are mandible and maxilla. Rarely presents metastasis, but the skull base, lymph nodes, and the lung are described as metastatic sites. Low recurrence rates were reported by the authors when surgical treatment achieved complete resection. Case Description: A female patient, 19 years old presenting moderate headache associated with nausea, vomiting, left facial hypoesthesia, and low visual acuity. Resonance image showed a heterogeneous expansive solid formation in sphenoid bone and clivus with neoplastic aspect. Signs of dissemination due to contiguity and invasion of skull base structures, especially cavernous sinus and internal carotid artery, determining also compression of the brainstem. First, an endoscopic biopsy was performed with otorhinolaryngology service. The pathological study showed histological characteristics of ameloblastoma. After, the patient was submitted to endoscopic surgery for resection of tumor. Conclusion: Ameloblastoma is a rare tumor with benign behavior and slow growing. It arises from odontogenic epithelium and accounts 1% of all oral tumors. The mandible and maxilla are the most common sites of origin. Ameloblastoma with intracranial involvement is a rare presentation with few literature reviews. A long time illness course and multiple surgeries are characteristics present in the majority of cases described. Total resection surgery is the treatment of choice and endoscopic transnasal resection is a viable option.

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Ameloblastoma and Intracranial Involvement: The Current Challenge of the Radical Surgical Treatment. Comprehensive Review of the Literature and Institution experience

Armocida

Berra

Pucci

et al. 2021

J. Maxillofac. Oral Surg.

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Background Ameloblastoma (AMBL) is an odontogenic tumor, considered to be benign, but aggressive, whose principal risk is a recurrence. The growth can be enormous, and it can extend into the intracranial compartment with serious consequences. Purpose The intracranial involvement of AMBL is rare, and it may require an extensive surgery. Although it is a rare condition for the neurosurgeon to treat, knowing this condition can lead to a significant increase in survival for these patients. Methods A case of a 56-year-old woman presented with a history of recurrent left maxilla AMBL with intracranial extension and dural involvement of the anterior and medial cranial fossa is reported, followed by a systematic review of the literature with the aim to identify the best surgical treatment. Results A total of 32 cases were included in the qualitative analysis. Management is varied and often not described, resulting in an almost complete lack of information and indications for treatment. Radical surgery tends to yield the best outcomes, and it is recommended to have adequate surgical margins when possible. Conclusions Intracranial involvement from AMBL compartment is an uncommon manifestation of this rare pathology, but which deserves to be treated in a multidisciplinary way in order to ensure maximum surgical radicality. Recurrence reflects failure of the primary surgical resection. If recurrence is the major consideration, surgeons are encouraged to select radical surgery. Whenever a follicular-type maxillary AMBL is diagnosed, it is advisable to check for intracranial spreading and distant metastases during follow-up.

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Intracranial Ameloblastoma Arising from the Maxilla: An Interdisciplinary Surgical Approach

Cited by 6 publications

References 23 publications

A Case Report with Literature Review: Recurrence of Peripheral Ameloblastoma with Intracranial Extension

A Case Report with Literature Review: Recurrence of Peripheral Ameloblastoma with Intracranial Extension

Pure endoscopic transsphenoidal treatment of skull base ameloblastoma with intracranial extension: Case report and literature review

Ameloblastoma and Intracranial Involvement: The Current Challenge of the Radical Surgical Treatment. Comprehensive Review of the Literature and Institution experience

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