Intracranial and orbital cavernous angiomas

Abstract

The authors review 30 documented cases of intracranial and orbital cavernous angiomas treated at their institution between 1965 and 1984. The diagnosis was based on computerized tomography (CT) or surgery; three patients were treated in the pre-CT era (1965 to 1976) and 27 since the advent of CT. The number of cases diagnosed preoperatively markedly increased after the introduction of CT, and 22 cases were verified histopathologically at surgery. Six cases were in children (aged 2 months to 17 years) and 24 in adults (aged 19 to 73 years). There was no significant sex difference (male:female ratio was 14:16). Nineteen lesions were intraparenchymal, five were intraventricular, three were in the middle fossa, two were intraorbital, and one originated from the tentorium. Symptoms varied according to the site of the lesion; hemorrhage occurred in 11 cases. Calcifications were seen on CT scans in all cases, but on plain skull films in only two. Angiography revealed hypovascular masses in all cases excluding those with lesions in the middle fossa; in two cases, tumor stain could be detected only with prolonged-injection angiography. Radionuclide brain scanning showed a dense hot area in eight of 19 patients. Recent experience has shown that magnetic resonance imaging clarified anatomic relationships that were obscure on CT. The overall outcome was favorable except for one patient who died in the postoperative period. The clinical results in this series are summarized and some diagnostic and therapeutic problems are discussed.

Unusual Progression of Pleomorphic Adenoma of the Lacrimal Gland-Case Report-

“…4,7,13) However, orbital bone destruction can occur even in cases of pseudotumor 3) or cholesterol granuloma. 6) If clinical evidence of intratumoral hemorrhage is found in a patient with an orbital tumor, malignancy should first be differentiated from other diseases such as cavernous angioma, 17,19) lymphangioma, 10) and cholesterol Unusual Progression of Lacrimal Pleomorphic Adenoma granuloma. 10) Pleomorphic adenoma is rarely associated with intratumoral hemorrhage.…”

İntraorbi̇tal Kavernöz Anji̇omlar

“…Literatürde bildirilen intrakranial ve intraorbital kavernöz anjiomlar içerisindeki intraorbital kavernöz anjiomların oranı % 6.6-9.2 arasmda değişmektedir (1,15). Kliniğimizde 1990 -Nisan 1994 yılları arasında tedavi edilen intrakranial ve intraorbital kavernöz anjiom olgularının toplam sayısı 29'dur.…”

“…Cerrahi eksizyonun amacı; kanama sonucu gelişen hematoma bağlı gör-me keskinliğinin giderilmesi, lezyonun histopatolojik natürünün tespit edilmesi ve yeniden kanamayı önlemeye yöneliktir (1,2,4,8,10,11,12,13,14,15). Orbital kavernöz anjiomlarda gelişen görme kaybının giderilmesi için cerrahi girişim geciktirilmemelidir.…”

Serebeller Kavernöz Anji̇omlar

“…Kavernöz anjiomlar klinik olarak % 60-70 oranında epilepsi, % 20 -25 oranında progresif nörolojik defisit, % 20-25 oranında da baş ağrı-sı şeklinde bulgu vermektedirler (3,10,11,13,14,15). Serebeller kavernöz anjiom olgularımızın tamamı, kanama ile birlikte ortaya çıkan baş ağrısı ve progresif nörolojik defisitlerinin gelişmesiyle kliniğimize baş-vurmuşlardır.…”