Intracranial aneurysms in pediatric population: a two-center audit

Garrido, Elisabeth; Metayer, Thomas; Borha, Alin; Langlois, Olivier; Curey, Sophie; Papagiannaki, Chrysanthi; Palma, Camille Di; Emery, Évelyne; Derrey, Stéphane; Gaberel, Thomas; Gilard, Vianney

doi:10.1007/s00381-021-05151-6

Cited by 14 publications

(16 citation statements)

References 57 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In our sample, giant aneurysms were found in ~ 27% of the cases, compatible with the 6-40% found in other series [2,7,8,13,22]. Regarding the location of the aneurysms, the ICA was the most common site (53%), as reported in several series [7,13,15], although some authors found MCA predominance [3,4]. Regarding the morphology, although most aneurysms were saccular and located in the anterior circulation, the rates of fusiform aneurysms (13%) and posterior circulation aneurysms (27%) are similar to literature, and higher when compared with adult series [1,2,3,15].…”

Section: Characteristics In Young-age Patientssupporting

confidence: 92%

Section: Characteristics In Young-age Patientssupporting

confidence: 87%

“…The aneurysms in childhood have a higher proportion of giant, fusiform and posterior circulation aneurysms than in adults [2,7,8,13,15,17]. In our sample, giant aneurysms were found in ~ 27% of the cases, compatible with the 6-40% found in other series [2,7,8,13,22]. Regarding the location of the aneurysms, the ICA was the most common site (53%), as reported in several series [7,13,15], although some authors found MCA predominance [3,4].…”

Section: Characteristics In Young-age Patientssupporting

confidence: 86%

“…The female predilection of aneurysms in adults is the opposite of what is seen in childhood. Most pediatric series found a male to female ratio ranging from 1.3 to 3.5:1 [1,7,8,13,18,21,22]. However, a slight female predominance (54%) was found in this study.…”

Section: Discussioncontrasting

confidence: 64%

“…Although embolization with coils has a higher recurrence rate than clipping [17], new endovascular technologies, such as ow diverting stents represent promising tools for vessel preservation [20,23]. Notwithstanding, independent of the treatment choice and considering the potential years of life, pediatric aneurysms have a higher recurrence rate and de novo aneurysm formation than adults; therefore, long term follow-up imaging is mandatory [1,7,8,22].…”

Section: Treatments and Outcomes In Young-age Aneurysm Patientsmentioning

confidence: 99%

See 4 more Smart Citations

Intracranial Aneurysms in the Pediatric Population: Case Series

Demart

Pardins

Koppe

et al. 2022

Preprint

View full text Add to dashboard Cite

Introduction: Aneurysms are rare in the pediatric population and its diagnosis can be challenging. They differ from their adult counterparts in several aspects, and hemorrhage is the most frequent presentation. Objective: To evaluate clinical data, aneurysms characteristics and therapeutic results in a series of patients <18 years of age with intracranial aneurysms. Method: A retrospective cross-sectional observational study design through the analysis of medical records and imaging studies. Analyzed data included age, sex, presentation, comorbidities, aneurysmal characteristics, treatment modality and clinical outcomes. Results: 15 intracranial aneurysms were identified in 11 patients (6 male), with ages ranging from 3 months to 15 years (mean 5.2 years). Five patients had associated medical conditions, and hemorrhage was the most frequent clinical presentation (45%). Three patients (27%) had multiple aneurysms, and 7 aneurysms were fusiform or dysplastic. The internal carotid artery was the most affected site, occurring in 47% of cases. Aneurysm size ranged from 2 mm to 60 mm (mean 16.8 mm), with giant aneurysms in 27%. Seven patients were treated via endovascular procedures and three aneurysms were clipped. Symptomatic vasospasm requiring angioplasty occurred in two patients. One patient died due to severe aspiration pneumonia and sepsis that precluded treatment. Good functional outcome (mRS < 2) was achieved in all patients submitted to treatment (91%). Conclusion: The patients with aneurysms in this series were characterized by hemorrhagic presentation, mild male predominance, and internal carotid artery involvement. The outcome of treated patients was favorable, regardless of the treatment modality.

show abstract