Intracranial intraparenchymal and intraventricular schwannomas: Report of 18 cases

Fractionated Radiosurgical Treatment of Intracerebral Schwannoma: A Case Report and Literature Review

“…The most common symptoms include headache, focal neurological signs, and seizures. [8][9][10] The histogenesis of ICS unrelated to cranial nerves is still unclear, although various theories have been postulated. In normal embryogenesis, Schwann cells are not normally present in the cerebral parenchyma.…”

“…12 Intracerebral schwannomas have been reported most commonly in the frontal, parietal, and occipital lobes and typically present with headache, signs of increased intracranial pressure, or focal seizures related to localization of tumor. 10,13,14 More than 85% of ICS are supratentorial, showing a predilection for periventricular or superficial localization. 15 Preoperative differential diagnoses include pilocytic astrocytoma, pleomorphic xanthoastrocytoma, ganglioglioma, meningioma, and glioblastoma.…”

“…15 Preoperative differential diagnoses include pilocytic astrocytoma, pleomorphic xanthoastrocytoma, ganglioglioma, meningioma, and glioblastoma. 10,16 Therefore, the primary treatment modality is often open surgery to gain histopathological verification and to select the right treatment modality.…”

Supra and infratentorial ectopic schwannoma mimicking a meningioma

“…About 70 cases of IES have been reported in the English literature,2 4 5 and these lesions seem to be mainly supratentorial in location, either superficial or periventricular. More rare locations of ectopic schwannomas have also been described such as third7 and fourth8 ventricle, intrasellar9 and pontomedulary cistern tumours with extension into dorsal spinal cord 10…”

“…Since Gibson et al 3 reported the first case of an intracerebral schwannoma located at the temporal lobe in 1966, about 70 cases have been reported in the English literature 2 4 5…”