Intracranial Malignant Triton Tumor in Children: A Case Report

Abstract

: Malignant triton tumor (MTT) is a rare, aggressive type of tumor that commonly originates from mesenchymal tissue and is mainly found in adults. Herein, we report a single case of a 12-year-old boy diagnosed with intracranial MTT. This report presents the clinical features and imaging findings of MTT. The 12-year-old patient consulted the hospital due to intermittent dizziness and headache. Computed tomography (CT) showed low-density space-occupying lesion in the left parietal fossa. Magnetic resonance imaging (MRI) showed a mass shadow with slightly long T1 and long T2 signal intensity in the same area. Contrast enhanced MRI (CE-MRI) showed obvious enhancement of the lesion. He was diagnosed with meningioma and underwent surgery. Postoperative histopathological examination diagnosed the lesion as MTT. Two months after the operation, CT examination showed tumor recurrence. He then underwent local radiotherapy and chemotherapy, and unfortunately, died six months later. Intracranial MTT should be considered as one of the differential diagnoses of intracranial meningiomas. CT and MRI are of great significance in the identification of lesion location, invasion range, and degree of malignancy. Final diagnosis of intracranial MTT requires histopathological examination. MTT has a poor prognosis, and surgical resection of the tumor is the preferred treatment. Intervention after early diagnosis is the key to improve the outcome of patients.

Case report: Primary intracranial EWs/PNET in adults: Clinical experience and literature review

“…MTT is usually equal and slightly hyperdense on CT, and a small volume of cystic necrosis is often seen. Tumors on MRI are mostly low signal on T1WI and high signal on T2WI, and arc or linear low-signal shadows appear in the high-signal tumor tissue, which is relatively specific for the diagnosis of MTT ( 35 ).…”

Clinical diagnostic and radiographic features of recurrent intracranial malignant triton tumor in an adult: illustrative case

“…MTT managed with multiple resections and several courses of chemoradiation, with the patient having markedly improved OS compared with historical cohorts. [10][11][12][13][14][15][16][17][18][19][20][21][22] Illustrative Case A 37-year-old female with a past medical history of Hodgkin lymphoma of the chest (diagnosed at age 12), status post-chemotherapy and radiation treatment to the chest, presented to an outside hospital (OSH) with acute-onset confusion, word-finding difficulty, disorientation, and right-sided weakness. Computed tomography (CT) of the head showed a left frontal dura-based mass with associated intraparenchymal hemorrhage and surrounding vasogenic edema.…”