Intracranial Melanotic Schwannomas

Spina, Alfio; Gagliardi, Filippo; Boari, Nicola; Terreni, Maria Rosa; Mortini, Pietro

doi:10.1055/s-0034-1393926

Cited by 12 publications

(10 citation statements)

References 47 publications

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“…The imaging findings of a primary intraspinal melanocytoma are characterized using short T1 and T2 signals (72%). 12 , 13 MRI in our patient showed T1 hypointensity and a short T2 signal in the vertebral bodies of C2 to C4. These results were consistent with an MRI diagnosis of MS.…”

Section: Discussionsupporting

confidence: 48%

“…Radiotherapy should be considered in cases of tumor recurrence, metastasis, histologic criteria of malignancy, or incomplete surgical resection. 3 , 12 Thus, even when adjuvant radiotherapy is administered to avoid relapse, close observation should be continued. Following the operation and adjuvant radiotherapy in the present case, the patient’s limb numbness and weakness were alleviated.…”

Section: Discussionmentioning

confidence: 99%

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Extramedullary melanotic schwannoma recurrence in the cervical vertebral arch: a case report and review of the literature

Hou

Shi

et al. 2020

J Int Med Res

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Melanotic schwannoma (MS), a slowly growing nerve sheath tumor, is not a purely benign tumor. MS accounts for less than 1% of all nerve sheath tumors. We herein describe a rare case of MS and present a literature review focusing on the treatment of this disease. Twelve years before presentation at our hospital, a 41-year-old woman was examined because of an 8-month history of neck pain and 6-month history of upper extremity numbness and weakness. She underwent surgery to remove a tumor, and the pathological examination confirmed a diagnosis of MS. Twelve years later, at 53 years of age, the patient presented to our hospital with a 2-year history of neck pain and upper extremity numbness and weakness. Posterior cervical tumor resection was performed along with posterior cervical laminectomy, decompression and intraspinal space-occupying internal fixation, and radiotherapy. MS recurrence was confirmed. No tumor recurrence or metastasis was found after 7 months of follow-up. Recurrence of MS is rare, and its diagnosis depends on pathological features. Radical excision is the primary treatment for MS. Incomplete resection of MS is a risk factor for postoperative recurrence and metastasis. Furthermore, postoperative adjuvant radiotherapy should be performed to prevent recurrence and metastasis of MS.

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Section: Discussionsupporting

confidence: 48%

Section: Discussionmentioning

confidence: 99%

Extramedullary melanotic schwannoma recurrence in the cervical vertebral arch: a case report and review of the literature

Hou

Shi

et al. 2020

J Int Med Res

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show abstract

“…Adjuvant radiotherapy remains controversial. Watson et al [1] suggested that, without histologic signs of malignancy, adjuvant treatment should not be performed and only strict radiologic and clinical follow-up is required. In our case, the tumor only presented a focally high Ki-67 index of 18%.…”

Section: Discussionmentioning

confidence: 99%

“…Our patient underwent a macroscopically complete resection. Vallat-Decouvelaere and Zhang [16] observed a lower rate of recurrence and metastases in patients with MS treated with adjuvant radiotherapy. According to these authors, radiotherapy should be considered in case of histologic criteria of malignancy, incomplete surgical resection, tumor recurrence, or metastases.…”

Section: Discussionmentioning

confidence: 99%

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