Intracranial Rosai Dorfman disease

Intracranial Rosai‑Dorfman disease complicated by mucosa‑associated lymphoid tissue: A case report

“…It is similar to meningioma in clinical and radiological aspects, so it is often misdiagnosed as a meningioma before surgery (12,16,22). Differential diagnosis includes meningiomas, eosinophilic granulomas, intracranial solitary fibrous tumors, plasma cell granulomas and dural metastases (12,23,24). For the patient in the present case, meningioma was also considered preoperatively.…”

“…Common extranodal sites of involvement include the skin and soft tissues (17%); the nasal cavity and sinuses (16%); the eyes, orbits and ocular appendages (11%); the skeletal system (11%); and the salivary glands (7%) (7,9). RDD of the central nervous system (CNS) is rare and accounts for <5% of reported RDD (10)(11)(12). Overall, ~75% of CNS RDD occur intracranially, while 25% involve the spine (13).…”

“…The imaging findings of intracranial RDD are similar to those of intracranial MALT lymphoma. The majority of the reported cases are located extra-axially and are closely associated with the meninges (12,15,16). There may be varying degrees of cerebral edema and meningeal enhancement and only a few cases show invasion of the brain parenchyma (17).…”

“…There may be varying degrees of cerebral edema and meningeal enhancement and only a few cases show invasion of the brain parenchyma (17). It is similar to meningioma in clinical and radiological aspects, so it is often misdiagnosed as a meningioma before surgery (12,16,22). Differential diagnosis includes meningiomas, eosinophilic granulomas, intracranial solitary fibrous tumors, plasma cell granulomas and dural metastases (12,23,24).…”

Commentary

“…In the current issue of journal of neurosciences in rural practice, the image and case reported entitled “Intra cranial Rosai-Dorfman disease” (RDD)[ 1 ] illustrates the main difficulty to reach the diagnosis of that rare non langerhans cell histiocytosis.…”