Intracystic papillary breast carcinoma in a male patient: a case report and review of literature

Abstract

Intracystic papillary carcinoma of the breast is a rare subtype of breast cancer accounting for approximately 0.5–1% of all breast carcinomas. To the best of our knowledge, the occurrence of this rare subtype of breast cancer in the male is even lower with less than 20 cases reported in the English literature over the past 30 years. We report a case of an elderly Asian male with intracystic papillary breast carcinoma who initially presented with a right sided breast lump for 4 months duration and his subsequent management. In addition, a review of similar cases in the English literature is included.

Symptomatic Benign Breast Cyst in a Young Male

“…Intracystic papillary breast carcinoma has been reported as many as 18 cases among males. 9 FNAC and trucut biopsy are also diagnostic in intracystic papillary breast carcinoma. As in ours, we chose to proceed with FNAC which has been proven to be benign.…”

“…An excisional biopsy is recommended in all cystic lesions in the male breast if the results are inconclusive. 9 Even though it is uncommon, breast cancer among males which accounts for only 1% of all breast malignancies can lead to significant morbidity and mortality. 10 In conclusion, breast cysts in males are extremely rare due to the physiological absence of lobular tissue.…”

Intraductal Papillary Carcinoma of the Breast: A Case Presentation

“…El papiloma intraductal es el grupo más frecuente de las lesiones papilares de la mama afectando hasta a un 5,3% de la población. Pueden ser papilomas centrales (retroareolares) o encontrarse en la periferie y se presentan como lesiones arborescentes centradas por un eje fibrovascular y revestidas por una capa de células mioepiteliales sobre las que se encuentra otra proliferación de células epiteliales [12].…”

“…El carcinoma papilar sólido, está compuesto por nidos sólidos, con finos ejes fibrovasculares en su interior que son difíciles de apreciar [12]. No es infrecuente la ausencia de celulas una fina capa de celulas epiteleales periféricas.…”

“…El carcinoma papilar intraductal, es raro pues se representa el 1 por ciento de los carcinomas mamarios, representa aproximadamente el 0,5-1% de todos los carcinomas de mama [12]. Se presenta en mujeres posmenopáusicas, con una edad promedio entre 64 y 67 años, pueden ser solitarios o múltiples, se localizan en la región retro alveolar o subalveolar como una masa solitaria de bordes bien definidos, aunque en ocasiones las mujeres pueden presentar telorragia en alrededor del 20 al 35 por ciento de los casos [7].…”