Intrahepatic abscesses: Amebic and pyogenic

Ribaudo, J. M.; Ochsner, Alton

doi:10.1016/0002-9610(73)90139-6

Cited by 31 publications

(22 citation statements)

References 9 publications

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“…This figure is closely paralleled by the 0.013% frequency reported from The Johns Hopkins Hospital in 1975 [12]. Many series report an average age in the sixth and seventh decades [8,9,12,17,20,27,28]. With improvement in diagnosis, however, the disease will likely become more common, reflecting the advanced chronicity and complexity of current diseases as well as more accurate diagnosis.…”

mentioning

confidence: 81%

“…Elevation of the serum bilirubin was present in 117 of 299 patients (39%). Elevations of bromsulphalein retention and erythrocyte sedimentation rate were found in over 50% of cases when measured [5,8]. Hirschowitz and others have stressed the importance of serum alkaline phosphatase elevation as an indicator of a hepatic space-occupying lesion [42,43].…”

Section: Clinical and Laboratory Featuresmentioning

confidence: 99%

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Pyogenic liver abscess

McDonald

Howard

1980

World j. surg.

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mentioning

confidence: 81%

Section: Clinical and Laboratory Featuresmentioning

confidence: 99%

Pyogenic liver abscess

McDonald

Howard

1980

World j. surg.

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“…7 Patients with negative culture results were continuously treated with same combination. 8 The antibiotic regime was not changed for patients with poor treatment response. Intravenous antibiotic therapy was continued for a minimum of 7 days in all patients.…”

Section: Antibiotics Policymentioning

confidence: 99%

Liver abscess drainage by needle aspiration versus pigtail catheter: a prospective study

Khan

Tekam

2017

Int Surg J

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Background: Liver abscess is a disease of frequent occurrence which figures prominently in the differential diagnosis of upper abdominal and right lower respiratory tract diseases. These includes a recent increase in incidence reflecting more accurate diagnostic techniques especially after 1965 with the advent of radioisotopes scan and later on ultrasonography and CT scan. The reduction in mortality from 90% at the turn of century to the estimated 10-20% today cannot be ascribed to surgery alone.Methods: The study was conducted on 65 patients of liver abscess. Two compared modalities of percutaneous treatment of liver abscess were (1) needle aspiration and (2) pigtail catheter aspiration. All interventions were performed under ultrasonographic guidance. Only those patients having liver abscess/abscesses greater than 5 cm in at least one dimension, liquified & drainable were included in this study.Results: Amoebic liver abscess (63.33%) were more common than pyogenic liver abscess (26.67%). Clinical recovery was significantly earlier in catheter group (average 5 days) than in needle aspiration group (average 6.29 days) (p value 0.001). Average duration of i.v. antibiotic is significantly shorter in catheter group (6.4 days) than in needle aspiration group (9.5 days) (p value 0.002).Conclusions: Thus, our study concluded that in view of greater volume of pus drained in first sitting, early clinical recovery, shorter duration of hospital stay and slightly more success rate continuous catheter drainage is effective percutaneous treatment modality than intermittent needle aspiration.

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“…However, due to the complications of liver abscess especially the amebic ones the morbidity is still high. 3,4 The management of liver abscess has always been a dilemma for the clinicians, whether to perform a therapeutic aspiration or to treat conservatively.…”

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confidence: 99%

Correlation between abscess size and liver function tests in cases of liver abscess

Jain¹,

Manjavkar²,

Rajput³

et al. 2017

Int J Res Med Sci

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Background: Liver abscess has shown a major change in demographics, etiology, diagnosis, and treatment over the past 100 years. The modern diagnostics like ultrasound and computed tomography to locate and drain the abscess have reduced the mortality to 2-12%. However, due to the complications of liver abscess especially the amebic ones the morbidity is still high. This study aims to study the correlation of various LFT parameters with abscess volume for early detection of high risk patients and early treatment thus reducing morbidity.Methods: The study was conducted over a period of 6 months on 50 patients of liver abscess. History and physical examination was done. All patients were subjected to complete hemogram, liver function test, coagulation profile (PT/INR) and USG abdomen. The data was recorded and compiled in excel sheets and analyzed using correlation coefficient (R) method.Results: The mean age of the patients was 41.2 years with male preponderance. Amoebic liver abscess (88%) was predominant over pyogenic liver abscess (12%). Alcoholism (48%), smoking (42%) and diabetes mellitus (18%) are main predisposing factors in case of liver abscess. Hepatomegaly was found in 88% cases. Elevated ALP, low albumin, increased PT INR points to the diagnosis of liver abscess. Complications seen were pleural effusion (10%) and ascites (4%). On analysis, liver abscess size is significantly positively correlated with INR, ALP, liver enzymes, and negatively correlated with serum albumin level.Conclusions: Liver abscess size was found to be positively correlated with INR and alkaline phosphatase (ALP), liver enzymes (SGOT, SGPT) and negatively correlated with serum albumin levels. There was no correlation of abscess size and bilirubin levels. Hence, LFT can be used to estimate the liver abscess size and predict the severity and prognosis of patient.

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Intrahepatic abscesses: Amebic and pyogenic

Cited by 31 publications

References 9 publications

Pyogenic liver abscess

Pyogenic liver abscess

Liver abscess drainage by needle aspiration versus pigtail catheter: a prospective study

Correlation between abscess size and liver function tests in cases of liver abscess

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