Intrahepatic bile duct exploration lithotomy is a useful adjunctive hepatectomy method for bilateral primary hepatolithiasis: an eight-year experience at a single centre

Li, Enliang; Yuan, Rongfa; Liao, Wenjun; Feng, Qian; Lei, Jun; Yin, Xin; Wu, Linquan; Shao, Jianghua

doi:10.1186/s12893-019-0480-1

Cited by 18 publications

(14 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…1 Therefore, bile duct exploration and lithotomy, combined with a reduced hepatectomy if necessary, will be an ideal surgical option. 61 There are few reports of laparoscopic surgery for the treatment of complicated bilateral hepatolithiasis. 58 In these reports, the immediate stone clearance rate is low, and the recurrence rate of hepatolithiasis is high.…”

Section: Laparoscopic Surgery For Complicated Hepatolithiasismentioning

confidence: 99%

Application of Laparoscopic Technique in the Treatment of Hepatolithiasis

Yao¹,

Wu²

2020

Surgical Laparoscopy, Endoscopy &Amp; Percutaneous Techniques

View full text Add to dashboard Cite

Hepatolithiasis is commonly encountered in Southeastern and East Asian countries, and its incidence is increasing in Western countries. For symptomatic hepatolithiasis or asymptomatic hepatolithiasis with signs of liver atrophy or malignancy, surgical intervention is needed, especially when peroral cholangioscopy and percutaneous transhepatic cholangioscopic lithotomy are not suitable or fail to be performed. Currently, laparoscopic surgery is gradually replacing traditional open surgery and becoming a better option. Various types of laparoscopic surgeries, including laparoscopic hepatectomy, laparoscopic biliary exploration through the common bile duct or the hepatic duct stump, and robotic-assisted laparoscopic surgery, have been developed for the treatment of simple hepatolithiasis, hepatolithiasis concomitant with choledocholithiasis, recurrent hepatolithiasis, and complicated hepatolithiasis. The related clinical experience is gradually accumulating. In this review, the laparoscopic applications and their advantages will be summarized. In most cases, the laparoscopic technique could provide the advantages of less trauma, reduced blood loss, and faster postoperative recovery.

show abstract

Section: Laparoscopic Surgery For Complicated Hepatolithiasismentioning

confidence: 99%

Application of Laparoscopic Technique in the Treatment of Hepatolithiasis

Yao¹,

Wu²

2020

Surgical Laparoscopy, Endoscopy &Amp; Percutaneous Techniques

View full text Add to dashboard Cite

show abstract

“…Hepatectomy is regarded as the best approach to treat hepatolithiasis because it can remove stones and expand the bile duct simultaneously [1] . Meanwhile, CBDE, endoscopic approaches, liver transplantation, chemical bile duct embolization, and a combination of these are effective methods for treating hepatolithiasis [11,14–16] . Due to the unique anatomical location, caudate lobe resection is technically challenging, especially for isolated caudactomy, because it is easy to damage the hilum and the inferior vena cava, which could potentially cause uncontrolled bleeding [17] .…”

Section: Discussionmentioning

confidence: 99%

“…[1] Meanwhile, CBDE, endoscopic approaches, liver transplantation, chemical bile duct embolization, and a combination of these are effective methods for treating hepatolithiasis. [11,[14][15][16] Due to the unique anatomical location, caudate lobe resection is technically challenging, especially for isolated caudactomy, because it is easy to damage the hilum and the inferior vena cava, which could potentially cause uncontrolled bleeding. [17] Herein, there was no simple caudate calculus, and all of them combined with multiple intrahepatic stones.…”

Section: Discussionmentioning

confidence: 99%

The postoperative choledochoscopy in the management of the residual hepatolithiasis involving the caudate lobe

Zhuang

Feng

et al. 2021

Medicine

View full text Add to dashboard Cite

To reveal the role of the postoperative choledochoscopy in treating the residual calculi in the caudate lobe (CL) of the liver. We recruited 66 patients with T-tube/percutaneous transhepatic cholangioscopy tract who still had residual gallstones in the CL at least 6 weeks after the operation. Imaging examinations determined the gallstones’ locations in the patients, and all of them underwent the postoperative choledochoscopic examination through the T-tube/percutaneous transhepatic cholangioscopy tract for therapeutic intervention. Among the 66 patients, the residual gallstones were mostly located in the Spiegel lobe (48/66, 72.7%), and the residual gallstones that located in the origin of the CL bile branches were successfully determined in the 57 patients (57/66, 86.4%), the remaining 9 patients were unclear because the proximal ducts were severely narrow or even atresia. The mean frequency of the postoperative choledochoscopy was 3.6 (range, 1–10) times. There were 9 patients with complications, and no mortality occurred. In the origin-proved 57 patients, 6 patients failed to remove the gallstones altogether, and the final residual gallstone clearance rate was 77.3% (51/66). There was no significant difference between the Spiegel lobe and the other parts of the CL in determining the bile duct's origins, gallstone clearance rate, and complications. However, the frequency of choledochoscopy in the other parts of the CL was more than in the Spiegel lobe. The postoperative choledochoscopy, an essential method for treating the residual gallstones in the CL, commands high efficiency for calculi extraction and fewer complications. The main reasons for failing to remove the residual gallstones are that the bile duct's origins could not be determined, and the distal bile ducts are atretic in the CL.

show abstract

“…Usually, open partial hepatectomy is used as an effective treatment for hepatolithiasis ( 20 ). The most frequent location of intrahepatic ductal stones in hepatolithiasis is in segments I-IV of Couinaud ( 21 ). With the development of minimally invasive concepts, technologies and anatomical features, laparoscopic partial left LLH has become widely used and established as a more effective treatment for hepatolithiasis ( 22 ).…”

Section: Discussionmentioning

confidence: 99%

The circRNA_102911/miR‑129‑5p/SOX6 axis is involved with T lymphocyte immune function in elderly patients with laparoscopic left hepatectomy for hepatolithiasis

Zhao

Xiao-yu²,

Liu

et al. 2020

Exp Ther Med

View full text Add to dashboard Cite

The aim of the present study was to investigate the impact of laparoscopic left hepatectomy (LLH) for hepatolithiasis on the T lymphocyte immune changes of elderly patients and to analyze underlying mechanisms of action behind these changes. A total of 164 patients who underwent LLH due to left-sided hepatolithiasis were recruited. In terms of T lymphocyte immune changes, it was found that firstly, the basic quantity of peripheral lymphocytes in the elderly group was significantly lower than that in a younger preoperative group. Secondly, after surgical trauma, the immune function of T lymphocytes had a significant decline and lasted longer when compared with younger patients, which was reflected by the perioperative changes in the T lymphocyte proliferative ability, levels of IL-2 secreted by T lymphocytes and the percentage of CD3 + /CD4 + T lymphocytes in the peripheral blood. Circular RNA (circRNA) 102911 (102911) was upregulated and microRNA (miR)-129-5p was downregulated in CD3 + /CD4 + T lymphocytes from elderly patients with LLH for hepatolithiasis. Furthermore, the overexpression of 102911 inhibited the proliferation of CD3 + /CD4 + T lymphocytes as well as promoting cell apoptosis, with the opposite effects being observed on knockdown of 102911. miR-129-5p is involved in the proliferation and apoptosis of CD3 + /CD4 + T lymphocytes and may be a promising target of 102911. Moreover, SOX6 is a downstream molecule of miR-129-5p. Immune function and number of T lymphocytes decreased significantly after surgical trauma compared to younger patients, and this decline lasted longer in older patients treated with LLH for hepatolithiasis. The 102911/miR-129-5p/SOX6 axis was found to be involved in T lymphocytes immune function, which provided a novel insight for the treatment of elderly patients with hepatolithiasis.

show abstract

Intrahepatic bile duct exploration lithotomy is a useful adjunctive hepatectomy method for bilateral primary hepatolithiasis: an eight-year experience at a single centre

Cited by 18 publications

References 19 publications

Application of Laparoscopic Technique in the Treatment of Hepatolithiasis

Application of Laparoscopic Technique in the Treatment of Hepatolithiasis

The postoperative choledochoscopy in the management of the residual hepatolithiasis involving the caudate lobe

The circRNA_102911/miR‑129‑5p/SOX6 axis is involved with T lymphocyte immune function in elderly patients with laparoscopic left hepatectomy for hepatolithiasis

Contact Info

Product

Resources

About