Intrahepatic Cholestasis of Pregnancy: The Usefulness of Serum Bile Acid Profile for Diagnosis and Treatment

Lucangioli, Silvia; Tripodi, Valeria

doi:10.5772/34123

Cited by 1 publication

(1 citation statement)

References 47 publications

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“…The hydrocarbon chain of UQ makes it highly lipid-soluble with a reported log P > 10. [3] In 1975, Mitchell discovered how UQ contributed to ATP synthesis. [4] Mitchell considered the formation of membrane potential as a result of proton gradient generation across the membrane which served as the driving force for ATP synthesis via oxidation and reduction of the coenzyme orientated across the membrane.…”

Section: Introductionmentioning

confidence: 99%

Ubiquinone electrochemistry in analysis and sensing

Conghaile

Arrigan

2022

Electrochemical Science Adv

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Ubiquinone (UQ) is a lipophilic compound present in most living organisms, where UQ's interesting but complex electrochemistry serves an important role in the transfer of electrons and protons within and across the mitochondrial membrane. We briefly review the electrochemical characteristics of UQ and its reduced state, ubiquinol, in solution and immobilized on electrodes, together with its application in electrochemical sensing and detection systems, for example, measuring redox status with reference to reactive oxidative species. The importance of the local environment, solvent, electrolyte, organic membrane, and pH, on the electrochemical behavior of UQ, is also discussed. We discuss techniques used for the direct detection of UQ such as liquid chromatographyelectrochemistry. Mediated electrochemistry of UQ allows for quantitative measurements of ions, small molecules, and other analytes such as glucose via chemical sensors and biosensors.

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Section: Introductionmentioning

confidence: 99%