2008
DOI: 10.4314/ajhs.v14i1.30851
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Intrahepatic expression of interferon alpha & interferon alpha receptor m-RNA can be used as predictors to interferon response in HCV and HCC patients

Abstract: Chronic hepatitis C Virus (HCV) is the leading cause of liver cirrhosis worldwide and in Egypt. Patients with cirrhosis secondary to chronic HCV infection are at increased risk for developing Hepatocellular carcinoma (HCC) in which Interferon therapy is the only effective anti-viral therapy. The current study aimed to investigate the expression IFN-α and IFN-α Receptor genes in liver biopsies from patients with HCV and HCC. Correlation of their expression with the clinical, histopathological progress of the di… Show more

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