Intrahepatic Splenosis with Severe Iron Deposition Presenting with Atypical Magnetic Resonance Images

Nakajima, Tomoki; Fujiwara, Atsushi; Yamaguchi, M.; Makiyama, Akiko; Wakae, Takeshi; Fujita, Kinya; Yoshikawa, Kunihiko; Shiomi, Takehiko; Ohishi, T; Nakashima, Tomoki; Konishi, Eiichi

doi:10.2169/internalmedicine.47.0689

“…If the splenic implant is intra-hepatic, CT imaging may show hypodense masses with strong enhancement at the early phase and pooling enhancement at delayed phase [9]. Grande et al described multiple well-demarcated nodules without calcifications, slightly hypodense compared to the liver at non-contrast CT, showing as lobular or oval well-circumscribed structures, hyperdense in the arterial phase and isodense in the portal phase after contrast administration [10].…”

Section: Discussionmentioning

confidence: 99%

RETRACTED ARTICLE: Benign splenosis mimicking peritoneal seeding in a bladder cancer patient: a case report

Rizzo

¹

,

Monfardini

²

,

Belmonte

³

et al. 2009

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IntroductionSplenosis is a post-traumatic autotrasplantation and proliferation of splenic tissue in ectopic sites. These implants may mimic malignancy in healthy patients or peritoneal metastases in cancer patients. When a previous history of splenic injury is known, the finding of soft tissue nodules in many thoracic and abdominal locations might raise the suspicion of the benign condition of splenosis, in order to avoid unnecessary surgery or chemotherapy.Case presentationA 56-year-old man with history of persistent hematuria from bladder cancer was referred to our Institution for suspected peritoneal carcinosis. For staging purposes he underwent abdominal computed tomography and ultrasound. The integration of patient's history and imaging results led to the diagnosis of peritoneal splenosis. The patient therefore underwent regular Trans Urethral Resection of Bladder for the known malignancy; while no treatment was necessary for splenosis. Two years follow-up was negative for metastases.ConclusionSplenosis is a benign condition after traumatic splenectomy which should be taken into account in the differential diagnosis with peritoneal seeding of malignancy because its appearance may resemble malignancy.

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“…Ultrasound may incidentally show hypoechoic masses on the surface of solid abdominal organs, such as the liver [9] or the kidney [5]. It may also show multiple solid masses with a smooth round or ovoid shape, with a homogeneous echo-texture and a hyperehoic peripheral rim, without specific arterial or venous Doppler signals [10].…”

Section: Discussionmentioning

confidence: 99%

Benign splenosis mimicking peritoneal seeding in a bladder cancer patient: a case report

Rizzo

¹

,

Monfardini

²

,

Belmonte

³

et al. 2009

Cases J

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IntroductionSplenosis is a post-traumatic autotrasplantation and proliferation of splenic tissue in ectopic sites. These implants may mimic malignancy in healthy patients or peritoneal metastases in cancer patients. When a previous history of splenic injury is known, the finding of soft tissue nodules in many thoracic and abdominal locations might raise the suspicion of the benign condition of splenosis, in order to avoid unnecessary surgery or chemotherapy.Case presentationA 56-year-old man with history of persistent hematuria from bladder cancer was referred to our Institution for suspected peritoneal carcinosis. For staging purposes he underwent abdominal computed tomography and ultrasound. The integration of patient's history and imaging results led to the diagnosis of peritoneal splenosis. The patient therefore underwent regular Trans Urethral Resection of Bladder for the known malignancy; while no treatment was necessary for splenosis. Two years follow-up was negative for metastases.ConclusionSplenosis is a benign condition after traumatic splenectomy which should be taken into account in the differential diagnosis with peritoneal seeding of malignancy because its appearance may resemble malignancy.

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“…39 Pancreatic acini were found intermingled with peribiliary glandular acini in 4% of autopsy livers, probably representing an intrinsic component of these glands. 40 Splenic heterotopia presenting as a mass lesion was reported by Lacerda et al 41 With one exception, 42 the rare cases recently reported are examples of splenosis or subcapsular splenic implants following trauma or surgical splenectomy 43 (see Chapter 16). Thyroid heterotopia has been occasionally encountered ( Fig.…”

Section: Heterotopias Of the Livermentioning

confidence: 97%

Developmental abnormalities and liver disease in childhood

Portmann¹,

Roberts²

2012

MacSween's Pathology of the Liver

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Intrahepatic Splenosis with Severe Iron Deposition Presenting with Atypical Magnetic Resonance Images

Abstract: An intrahepatic mass was incidentally found in a 41-year-old

Cited by 28 publications

References 20 publications

RETRACTED ARTICLE: Benign splenosis mimicking peritoneal seeding in a bladder cancer patient: a case report

RETRACTED ARTICLE: Benign splenosis mimicking peritoneal seeding in a bladder cancer patient: a case report

Benign splenosis mimicking peritoneal seeding in a bladder cancer patient: a case report

Developmental abnormalities and liver disease in childhood

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