2019
DOI: 10.1111/evj.13111
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Intralesional application of medical grade honey improves healing of surgically treated lacerations in horses

Abstract: Summary Background Infection and dehiscence of simple lacerations is common in horses, and consistently effective methods of prevention are yet to be found. Honey has been shown to promote wound healing when applied topically; however, intralesional application prior to wound closure has not been reported. Objectives To examine whether intralesional application of medical grade honey (MGH) would reduce the incidence of infection and dehiscence following wound closure. Study design Prospective, open‐label rando… Show more

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Cited by 25 publications
(30 citation statements)
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“…Together, these characteristics make MGH effective against a broad range of microorganisms, including those resistant against antibiotics . MGH can serve as an alternative or complementary treatment for antibiotics in local infections, but also its prophylactic use has been demonstrated . Moreover, MGH has pro‐healing effects, keeps the wound moisturized, promotes autolytic debridement, has anti‐inflammatory and antioxidative effects, and induces angiogenesis and reepithelialization .…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…Together, these characteristics make MGH effective against a broad range of microorganisms, including those resistant against antibiotics . MGH can serve as an alternative or complementary treatment for antibiotics in local infections, but also its prophylactic use has been demonstrated . Moreover, MGH has pro‐healing effects, keeps the wound moisturized, promotes autolytic debridement, has anti‐inflammatory and antioxidative effects, and induces angiogenesis and reepithelialization .…”
Section: Introductionmentioning
confidence: 99%
“…3 MGH can serve as an alternative or complementary treatment for antibiotics in local infections, but also its prophylactic use has been demonstrated. 12 Moreover, MGH has pro-healing effects, keeps the wound moisturized, promotes autolytic debridement, has anti-inflammatory and antioxidative effects, and induces angiogenesis and reepithelialization. 1,2,[13][14][15] Honey also contains protective molecules such as phenolic compounds and flavonoids that further enhance wound healing.…”
Section: Introductionmentioning
confidence: 99%
“…42 In a randomized controlled trial with 127 horses having lacerations, MGH1 was able to prevent infections and improve complete healing and veterinarian satisfaction. 43 Infected wounds often contain polymicrobial pathogens 44,45 and therefore an antimicrobial agent active against a wide spectrum of pathogens is warranted. The broad response of almost all the isolates tested in the present work against both MGHs suggests that they might have therapeutic efficacy in a variety of pathologies and that it should be considered for treatment of wounds and otitis externa.…”
Section: Discussionmentioning
confidence: 99%
“…In parallel, manuka honey has been utilised by on October 29, 2020 by guest http://aem.asm.org/ Downloaded from the veterinary community, in particular for treatment of equine wounds [16]. Previous work has demonstrated in vitro activity against a wide range of equine bacterial isolates [17] with in vivo activity also recently reported [18].…”
Section: Downloaded Frommentioning
confidence: 99%