Intralesional Injection of Ethanolamine Oleate With or Without Local Anaesthetic Agent to Assess Postoperative Pain in Oral Venous Malformations (A Randomized Controlled Clinical Trial)

Abstract

INTRODUCTION:Sclerotherapy is an established treatment modality for oral vascular anomalies. A sclerosing agent such as Ethanolamine Oleate has been widely used for oral vascular malformation, especially low-flow venous lesions, however, pain is one of the most common postoperative complications. Therefore, Ethanolamine Oleate with an anesthetic agent may help in reducing postoperative pain in cases of oral venous malformation. AIM OF THE STUDY:To compare the effect of Ethanolamine Oleate as a sclerosing agent for oral venous malformation with and without an anesthetic agent in reducing postoperative pain and resolution of the lesion. MATERIALS AND METHODS: 16 patients with oral venous malformation were recruited and randomly allocated into two equal groups. Sclerotherapy with Ethanolamine Oleate was performed for all patients in Group A (Control Group) eight patients were injected with Ethanolamine Oleate alone and for Group B (Study Group) eight patients were injected with Ethanolamine Oleate mixed with Lidocaine. RESULTS: There was a statistically significant decrease between the two studied groups. Using the VAS scale, showed a significant decrease in post-operative pain reaching an (87.5%) success rate in Group B, especially two days postoperatively. CONCLUSION: This study confirmed the positive effect of intralesional injection of EO and Lidocaine in OVMs regarding postoperative pain and resolution of the lesion.