Intralesional Sclerotherapy in the Management of Hemangiomas of the Glans Penis

Abstract

Intralesional sclerotherapy is a cost-effective modality for the treatment of glans penis hemangiomas, especially in developing countries and at peripheral hospitals where expensive laser equipment may not be available.

Role of Intralesional Bleomycin in the Treatment of Complicated Hemangiomas: Prospective Clinical Study

“…Hemel and colleagues treated four cases of penile hemangiomas with sclerotherapy (30% hypertonic solution) and concluded that the technique is safe, manageable, and inexpensive 25 …”

An unusual cause of paraphimosis: hemangioma of the glans penis

“…Because it can be applied within a few seconds under local anesthesia with favorable cosmetic results, it should be considered in small hemangiomas or adjuvant to the other treatment modalities [8]. Successful sclerotherapy with intralesional injection of 30% hypertonic saline has been reported by Hemal et al in 4 patients with penile hemangioma [11]. They conclude that intralesional sclerotherapy is a cost-effective modality in case of the unavailability of other techniques such as electrofulguration or laser coagulation.…”

“…Furthermore, it should be considered for voluminous hemangiomas as well. The risk of large volume of skin loss or development of the undesirable scar tissue formation replaced the surgical option with fulguration of the lesion, cryosurgery, laser ablation, or sclerotherapy [9,[11][12][13]. Laser therapy is a safe method in the treatment of vascular lesions of children [14].…”

Sclerotherapy for Penile Venous Malformations

“…Nd:YAG laser treatment has been reported to be effective and safe; however, it is associated with a high risk of scarring and a high incidence of recurrence 10,11 . Sclerotherapy has recently been reported as a good option in the treatment of vascular malformations and has provided excellent aesthetic and functional results even for lesions situated on the glans 4–7 . Direct intralesional injection of a sclerosing agent makes it possible to obliterate blood vessels by local endothelial destruction, with sludging of red blood cells and subsequent thrombosis, eventually leading to intimal fibrosis.…”

“…Although they are usually small in size and of little clinical importance, they may give rise to psychological discomfort and occasionally require emergency surgery if traumatized 1–3 . Therapeutic options include surgery, electrofulguration, cryotherapy, and recently laser treatment and sclerotherapy 4–7 . Sclerotherapy seems to be effective and economical, with fewer risks than other treatments; although being new, it has been used in a relatively small number of cases and never in dermatology 4–7 .…”