Intralumen Pressures of the Digestive Tract, Especially the Pyloric Region

Brody, Daniel A.; Werle, J. M.; Meschan, I.; Quigley, James P.

doi:10.1152/ajplegacy.1940.130.4.791

Cited by 38 publications

(13 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…All 3 portions of the pyloric region were inhibited in a similar manner by duodenal distention, but stretching the other parts of the digestive tract was slightly less effective on the duodenal bulb than on the antrum or sphincter. with pressures of 5 to 15 mm., produced a slight increase in tone and motility of the sphincter region, similar to that previously reported (25,26). With higher pressures, up to 45 cm., an inhibition of the sphincter region frequently developed.…”

supporting

confidence: 89%

“…Therefore, we determined (22 experiments), by the x-ray method, the effects of noxious bodily stimuli on gastric evacuation and on gastric and bulbar motility. We checked these observations by the simultaneous registration of the activity of the pyloric sphincter, as recorded with the pyloric diagraph (28), and by the accurate determination of the intralumen pressures in the antrum and bulb (25). Studies with the pyloric diagraph alone were also made (8 experiments) to provide rather direct information regarding sphincter activity (actually, the changes in the external (serosal) diameter of the sphincter), while the lumen of the sphincter region was free of foreign bodies.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Evidence That Body Irritations or Emotions Retard Gastric Evacuation, Not by Producing Pylorospasm but by Depressing Gastric Motility 1

Quigley¹,

Bavor²,

Read³

et al. 1943

J. Clin. Invest.

Self Cite

View full text Add to dashboard Cite

supporting

confidence: 89%

mentioning

confidence: 99%

Evidence That Body Irritations or Emotions Retard Gastric Evacuation, Not by Producing Pylorospasm but by Depressing Gastric Motility 1

Quigley¹,

Bavor²,

Read³

et al. 1943

J. Clin. Invest.

Self Cite

View full text Add to dashboard Cite

“…Further errors may be introduced by using large balloons in an organ of irregular outlines (such as the stomach), where a symmetrical balloon may at one time be affected by the actual intraluminal pressure of the organ, while at other times it is compressed by the walls of the hollow viscus. Furthermore, as Quigley and his associates (6) have pointed out, the large balloons usually employed, whether elastic or of relatively fixed volume, do not measure intraluminal pressure, but merely indicate intestinal activity by changes in the volume or the pressure within the balloon.…”

Section: Discussionmentioning

confidence: 99%

The Motility of the Small Intestine in Sprue 1

Ingelfinger¹,

Moss²

1943

J. Clin. Invest.

View full text Add to dashboard Cite

An abnormal small-intestinal pattern has been demonstrated by roentgenologic studies in both the tropical and non-tropical variety of sprue (1 to 3). Generalized hypomotility is observed, and the barium moves along the gut in thick, sausageshaped masses which are separated by intestinal areas, apparently in a state of spasm. Many of the bowel loops are widely dilated and often contain considerable gas. At the same time, the mucosal relief is strikingly altered in that the usual markings of the valvulae conniventes are thickened, widely separated, and, in advanced cases, completely obliterated. In an admirable review of this subject, Golden (4) has, however, reiterated the original contention of Snell and Camp (1) that the observed changes are not characteristic of sprue, but may occur in other chronic deficiency states and, at times, may appear as the result of emotional stresses.In 2 patients with sprue, whom we repeatedly intubated over a period of 8 and 13 months, respectively, the small-intestinal motor activity was studied by means of the balloon-kymograph method, described by Ingelfinger and Abbott (5). Of the 2 patients, the first would be considered to have the tropical, the second, the non-tropical vanety of sprue.CASE REPORTS Case 1. W. C., a 36-year-old man, first noticed loose stools at the age of 21, shortly after he had been purser for 6 months on a boat sailing between New York and South America. Since that time, he had suffered from intermittent bouts of weight loss, distension, cramps, and frequent bowel movements, consisting of light stools never containing blood or pus. In the year before entry to this hospital, he had been subjected to 3 ileostomies in an effort to relieve his distension and cramps.Physical examination on July 18, 1941, revealed an emaciated individual with extreme hypotonia of the entire musculature. A brown pigmentation covered the forehead, cheilosis was present, and the tongue appeared dark red and smooth. The abdomen was markedly distended and tympanitic. Both a proximal and a distal ileostomy

show abstract

“…Hitherto, the mechanical activity of the gastroduodenal junction was only studied by recording intraluminal pressure (Wheelon & Thomas, 1922;Alvarez & Mahoney, 1923;Thomas & Crider, 1935;Meschan & Quigley, 1938;Brody, Werle, Meschan & Quigley, 1940;Carlson, Code & Nelson, 1966). Strain gauge transducers or induction coils were not yet used to study the correlation between pyloric and duodenal contractions.…”

Section: Introductionmentioning

confidence: 99%

Computer Analysis of Mechanical Activity of Gastroduodenal Junction in Unanaesthetized Dogs

Ehrlein

Hiesinger

1982

Exp Physiol

View full text Add to dashboard Cite

SUMMARYIn four conscious dogs mechanical activity of the gastroduodenal junction was recorded with chronically implanted strain gauge transducers and induction coils. The data were evaluated by a computer. Analog circuits were used in order to reduce the data which were transferred to the computer. In the digestive state the contractions of the pyloric sphincter and duodenal bulb were correlated in such a way that the contractions of the duodenal bulb were inhibited when the gastric waves travelled across the antrum and that the bulb contracted once or twice when the peristaltic waves arrived at the gastroduodenal junction. However, the timing between pyloric and duodenal contractions was imperfect. Contraction maxima of the duodenal bulb often occurred before the pylorus was closed. This was due to the different inherent frequencies of the pyloric and duodenal contractions. In the interdigestive state the timing between the pyloric and duodenal contractions was as imperfect as during the digestive state. In phase III of the interdigestive activity, however, the strong antral contractions were regularly associated with inhibition of the duodenal bulb. This phenomenon can be interpreted as co-ordination between gastric and duodenal activity.

show abstract

Intralumen Pressures of the Digestive Tract, Especially the Pyloric Region

Cited by 38 publications

References 0 publications

Evidence That Body Irritations or Emotions Retard Gastric Evacuation, Not by Producing Pylorospasm but by Depressing Gastric Motility 1

Evidence That Body Irritations or Emotions Retard Gastric Evacuation, Not by Producing Pylorospasm but by Depressing Gastric Motility 1

The Motility of the Small Intestine in Sprue 1

Computer Analysis of Mechanical Activity of Gastroduodenal Junction in Unanaesthetized Dogs

Contact Info

Product

Resources

About