Intramammary Propolis Formulation for Subclinical Mastitis Prevention and Treatment in Dairy Cows

Bačić, Goran

doi:10.15406/jdvar.2016.03.00091

Cited by 2 publications

(3 citation statements)

References 1 publication

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Section: Apitherapymentioning

confidence: 99%

“…These activities in mammary gland makes propolis great alternative to conventional therapy, and some reports proved it is even more effective against Gram-positive bacteria than Gram-negative bacteria [107][108][109]. Propolis have ability to even reduce the growth of typical mastitis pathogen like S. aureus to an average of zero [107], but to reduce reaction of mammary tissue concentration must be lower [108]. Surprisingly, even honeybee venom usually utilised as pain reliver and in treatment of inflammatory diseases is highly effective against typical mastitis pathogens including methicillin-resistant S. aureus (MRSA) without side effects even in its lowest concentrations [110,111].…”

Section: Apitherapymentioning

confidence: 99%

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Antimicrobial Resistance of Cattle Mastitis-Causing Bacteria: How to Treat?

Maksimović,

Čengić,

Ćutuk

et al. 2024

Veterinary Medicine and Science

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Cattle mastitis continues to be a global burden for the dairy industry, and its control depends on preventive measures, rapid detection and identification of involved pathogens and accurate antimicrobial treatment. The (mis)use of antimicrobials initiated a rapid evolutionary process of bacterial resistance by natural selection and led to the increased frequency and spread of bacterial antimicrobial resistance (AMR). The global AMR emergency and the prudent use of antimicrobials in cows have raised questions about alternative treatment approaches; however, the use of antimicrobials remains the principal method for mastitis therapy. This chapter summarise the current knowledge on AMR in cattle mastitis as a multifactorial global problem, the trends in AMR patterns in the most common mastitis-causing bacterial pathogens and altering factors, the policies and actions restricting the use of antimicrobials in cows and related challenges in the treatment. The reasons influencing the outcome of treating an intramammary infection, such as the selection of appropriate antimicrobial agents, optimal drug regimens, the gaps in antimicrobial susceptibility testing (AST) of mastitis pathogens and interpretation criteria, and the paradoxical relationship between antimicrobial in vitro activity and in vivo efficacy are discussed. The importance of effective mastitis control programmes is emphasised by an overview of (accurate) diagnosis, the evaluation of the therapy, cow health control and farm management practices.

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Section: Apitherapymentioning

confidence: 99%

Section: Apitherapymentioning

confidence: 99%

Antimicrobial Resistance of Cattle Mastitis-Causing Bacteria: How to Treat?

Maksimović,

Čengić,

Ćutuk

et al. 2024

Veterinary Medicine and Science

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“…Due to its antimicrobial, anti-inflammatory, and local antioxidant activities in the udder, propolis can control mastitis in cattle (Wang et al, 2016;Šuran et al, 2020). Intramammary infusion with 1% propolis formulation induced satisfactory antibacterial and antioxidant effects in dairy cows (Bacic et al, 2016;Šuran et al, 2020). Therefore, propolis may alternate the conventional antimicrobial drugs used to prevent and control subclinical mastitis in dairy cattle.…”

Section: Infectious Diseasesmentioning

confidence: 99%

Potential Benefits of Propolis in Large and Small Animal Practices: A Narrative Review of the Literature

Abu-Seida

2023

WVJ

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Propolis is a resinous substance from a mixture of different plant parts and molecules bees compose. This narrative review article explored the application of propolis in large and small animal practices in PubMed, Scopus, and Google Scholar databases. Propolis is applied in different pharmaceutical forms. Due to its numerous biological actions, such as antimicrobial, anti-inflammatory, antioxidant, antiparasitic, antiulcer, antitumor, and immunomodulatory, propolis can improve animal health and production. Propolis could be used as an alternative treatment for many diseases, such as mastitis, lumpy skin disease, foot and mouth disease, reproductive disorders, and diarrhea in cattle. Moreover, it could improve weight gain in cattle. In equine, propolis has been used as a local anesthetic and for treating dermatomycosis, chronic bronchitis, and skin wounds. In pigs, propolis has been used to treat enzootic pneumonia and as a prophylaxis for gastrointestinal and respiratory diseases in weak pigs. Propolis has been applied to treat caseous lymphadenitis and parasitic diseases in sheep and goats. Furthermore, it improves the immune status of kids and the health status of late pregnant ewes. In dogs and cats, propolis has been applied to treat otitis externa, eye diseases, Cushing’s syndrome, and dermatophytosis. In dogs, propolis can treat transmissible venereal tumors. Moreover, propolis positively affects animal production, average daily gain and milk yield in sheep, growth of calves, lambs, and piglets, and cow’s milk nutritional quality. On the other hand, the addition of propolis to the diet of feedlot bulls and pigs has no effect on their feed intake, hematological, biochemical, and immunological parameters, nutrient digestibility, microbial synthesis, and carcass characteristics. Based on the available clinical studies, propolis has potential benefits for animal health in cattle, equine, sheep, goats, pigs, dogs, and cats. According to the available literature, propolis is a natural promising agent that can alternate conventional pharmaceuticals, particularly antibiotics. It improves animal health and production with no adverse effects and low cost. Most conducted studies on the efficacy of propolis on animal health and production are in vitro. Due to its scarcity, further controlled clinical trials are recommended to evaluate the exact usefulness of propolis in veterinary medicine and to obtain reliable conclusions on the benefits of propolis in animal health and production.

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Intramammary Propolis Formulation for Subclinical Mastitis Prevention and Treatment in Dairy Cows

Cited by 2 publications

References 1 publication

Antimicrobial Resistance of Cattle Mastitis-Causing Bacteria: How to Treat?

Antimicrobial Resistance of Cattle Mastitis-Causing Bacteria: How to Treat?

Potential Benefits of Propolis in Large and Small Animal Practices: A Narrative Review of the Literature

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