Intramedullary Nail Fixation of Fibular Fractures Associated With Tibial Shaft and Pilon Fractures

Stewart, Christopher M.; Kiner, Dirk; Nowotarski, Peter J.

doi:10.1097/bot.0b013e3182694a2d

Cited by 19 publications

(21 citation statements)

References 12 publications

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“…Asloum et al 15 reported a 100% rate of union in 36 patients treated with intramedullary nail fixation. A union rate of 100% was also found by Stewart et al 41 using a retrograde intramedullary nail. Intramedullary nail fixation of distal fibula fractures has been heavily discussed in the recent literature, largely with positive outcomes.…”

Section: Discussionsupporting

confidence: 59%

Cannulated Intramedullary Screw Fixation of Distal Fibular Fractures

Ebraheim

Maten

Delaney

et al. 2018

Foot & Ankle Specialist

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Section: Discussionsupporting

confidence: 59%

Cannulated Intramedullary Screw Fixation of Distal Fibular Fractures

Ebraheim

Maten

Delaney

et al. 2018

Foot & Ankle Specialist

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“…Bone is one of the tissues that can heal without fibrous scar formation and bone healing occurs by tissue regeneration [Marsell and Einhorn, ]. In an attempt to recover full function and restore the anatomy, several treatment methods have been employed for treatment of fracture, including intramedullary nail fixation, plate and screw fixation, and surgical fixation [Drobetz et al, ; Stewart et al, ; Baldwin et al, ]. However, these methods are associated with highly variable outcomes, especially in elderly populations.…”

mentioning

confidence: 99%

The influence of MicroRNA‐150 in Osteoblast Matrix Mineralization

Dong

Liu

Zhang

et al. 2015

J of Cellular Biochemistry

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This study investigated the influence of miR-150 expression on osteoblast matrix mineralization and its mechanisms. The mouse osteoblast cell line MC3T3-E1 was used as an in vitro model of bone formation. On the fifth day of mineralization, transfection experiments using agomiR-150, agomiR-NC, antagomiR-150 antagomiR-NC, and mock groups were set up to test the effects of miR-150 in MC3T3-E1 model. The mRNA and protein levels of OC, ALP, type I collagen, and OPN were measured by qRT-PCR and ELISA. Matrix mineralization was detected by alizarin red S (ARS) staining and flow cytometry was employed to quantify apoptosis in each group. RT-PCR and Western blot were applied to detect the expression of target gene MMP14. Our results demonstrated that the endogenous expression levels of miR-150, OC, ALP, type I collagen, and OPN in MC3T3-E1 cells increased steadily. Exogenous expressions of agomiR-150 and antagomiR-150 can significantly up-/down-regulate, respectively, the expression level of miR-150 in MC3T3-E1 cells. Compared with the mock group, higher expression levels of OC, ALP, type I collagen, and OPN mRNA were observed in the agomiR-150 group, while lower mRNA expression levels of OC, ALP, type I collagen, and OPN were found in the antagomiR-150 group. Based on these results, potential miR-150 targeted genes are discussed. Our results showed that miR-150 supports the osteoblastic phenotype related to osteoblast function and bone mineralization. Thus, miR-150 may have potential therapeutic applications in promoting bone formation in certain disease settings, such as in osteoporosis and in elderly patients.

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“…We fixed fibula in all cases either with plating or intramedullary rod. Christopher et al [16] reported that an intact fibula or fibular plate fixation provides initial rotational stability and minimizes varus or valgus angulation in distal tibia fractures treated with either nailing and plating group [16]. 65% were closed and 35% grade 1 open type in group 1 cases compared to 55% closed and 45% grade 1 open in group 2.…”

Section: Discussionmentioning

confidence: 99%

Comparative Study Between Intramedulary Interlock Nailing and Plating in Distal Metaphyseal Fractures of Tibia

Hattarki¹,

Bhagat²

2016

Surgery Curr Res

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Distal metaphyseal tibial fractures are unique. Fractures of distal tibia metaphysis occur typically as a result of axial and rotational forces on lower extremity and represents approximately 10% of the fractures of distal end of tibia. Objective: The present study aims to compare the functional outcomes of distal metaphyseal fractures of tibia with plating to that with reamed intramedullary nailing and complication arising with different modalities of fixation. Methodology:The study consist of 40 patients of distal metaphysical fracture of tibia consecutively treated in the period between Dec 2013 and Dec 2015 with either reamed intramedullary nailing or locked plating with open reduction method or minimally invasive techniques. Results: Mean age of patients was 41.3 years (range, 22-65) in group 1 and 39.45 years (range, 28-56) in group 2 (p = 0.558). The average time before union was 23.3 weeks (range, 16-36 weeks) in group 1 and 25.55 weeks (range,14-41 weeks) in group 2, (p = 0.299). Conclusion: Intramedullary nail being load sharing device, comparatively early mobilization can be started. Prolonged duration of protected weight bearing was required in patients treated with locked plate and screws.

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Intramedullary Nail Fixation of Fibular Fractures Associated With Tibial Shaft and Pilon Fractures

Cited by 19 publications

References 12 publications

Cannulated Intramedullary Screw Fixation of Distal Fibular Fractures

Cannulated Intramedullary Screw Fixation of Distal Fibular Fractures

The influence of MicroRNA‐150 in Osteoblast Matrix Mineralization

Comparative Study Between Intramedulary Interlock Nailing and Plating in Distal Metaphyseal Fractures of Tibia

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