Intramedullary nailing for subtrochanteric fracture in autosomal dominant Type II osteopetrosis

Kim, Junyoung; Park, Young Chang; Moon, Hyun Soo; Do, Woo Sung; Yang, Kyu Hyun

doi:10.1097/md.0000000000021648

Cited by 10 publications

(5 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Studies have shown that after the use of cerclage wire, vascular supply is conserved [ 29 ]. As a result, if the application of the subtrochanteric cerclage wire is helpful for anatomical fracture reduction and stabilization, it is safe and valuable [ 30 ]. By providing the medial cortex, the cerclage wire sustains and accelerates the healing of the medial cortex.…”

Section: Discussionmentioning

confidence: 99%

The Clinical Efficacy of Minimally Invasive Clamp-Assisted Reduction and Open Reduction with Wire Cerclage for Unstable Subtrochanteric Fractures

Liu

et al. 2022

Journal of Healthcare Engineering

View full text Add to dashboard Cite

The purpose of this study was to compare the clinical effectiveness of minimally invasive clamp-assisted reduction and open reduction with wire cerclage and intramedullary nails for unstable subtrochanteric fractures. Between January 2016 and October 2019, 68 patients who had unstable subtrochanteric fractures experienced intramedullary nail surgery in this retrospective study. There were 41 cases in the minimally invasive clamp or closed reduction group (group A) and 27 cases in the open reduction with wire cerclage group (group B). There were 3 cases of complications in group A and 2 cases of complications in group B. Remarkable distinction was observed between the two groups in the operation time ( p < 0.05 ), quality of reduction ( p < 0.05 ), and union time ( p < 0.05 ). For the successful surgical treatment of unstable femoral subtrochanteric fractures, an anatomical reduction is crucial. Reduction and wire cerclage are cut to give medial support for the anatomical reduction, which has a positive effect on fracture healing.

show abstract

Section: Discussionmentioning

confidence: 99%

The Clinical Efficacy of Minimally Invasive Clamp-Assisted Reduction and Open Reduction with Wire Cerclage for Unstable Subtrochanteric Fractures

Liu

et al. 2022

Journal of Healthcare Engineering

View full text Add to dashboard Cite

show abstract

“…During the follow-up, they found that 2.5 years after the injury, the subtrochanteric fracture was united and in slight varus and external rotation. Furthermore, Kim et al [ 13 ] employed the intramedullary nailing (IMN) approach to treat two cases of adult osteopetrosis with subtrochanteric fractures. In the first case, IMN left a gap at the fracture site because the distal fragment was not effectively reamed, and the patient showed delayed union and subsequently underwent a dynamization procedure 6 mo postoperatively, which resulted in bone healing 10 mo after the dynamization.…”

Section: Discussionmentioning

confidence: 99%

“…The hard-done work of our peers has highlighted that the risk of the aforementioned delayed postoperative union and the nonunion associated with impaired bone remodeling[ 13 , 20 ]. To elaborate, Matsuo et al [ 21 ] reported the case of an osteopetrosis patient presenting with a femoral shaft fracture below a plate who underwent open reduction and internal fixation with locking plate and wire cerclage.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Treatment for subtrochanteric fracture and subsequent nonunion in an adult patient with osteopetrosis: A case report and review of the literature

Yang¹,

Shao²,

Du³

2021

WJCC

View full text Add to dashboard Cite

BACKGROUND As a congenital metabolic bone disease caused by defective osteoclastic resorption of immature bone, osteopetrosis is characterized by diffused sclerosis of bones, brittle bones, easy fracturing, narrow medullary canals, and a weak fracture healing ability. At present, clear standards and principles for the treatment of fractures in patients with osteopetrosis are lacking. Non-operative treatment can prevent fracture hematoma and preserve the blood supply to the bone fragments, while being associated with frequent failures and higher mortality rates. Meanwhile, closed reduction and internal fixation with intramedullary nail (CRIF + IMN) approaches can also protect blood supply to the fracture site. However, IMN cannot be used for the vast majority of patients with osteopetrosis due to the narrowing of medullary canals. Thus, open reduction and internal fixation with plate remains the most appropriate surgical method for treating fractures in patients with osteopetrosis, but this approach is complicated by the lack of intramedullary hematopoiesis in such patients. Fracture healing primarily depends on the blood supply to the external periosteum. Open reduction can also easily destroy the periosteum and cause delayed fracture healing or even nonunion; however, CRIF may be the most practical approach. As a result, it would be prudent to solve the difficulty of drilling during the operation and the problem of postoperative nonunion. CASE SUMMARY In 2018, we treated an adult patient with osteopetrosis presenting with a subtrochanteric fracture. The fracture was fixed using a femoral locking compression plate. Because of delayed consolidation, at 12 mo postoperatively the patient was further treated with platelet-rich plasma (PRP) combined with radial extracorporeal shock wave therapy (rESWT). Antero-posterior and lateral radiographs obtained at the latest follow-up (10 mo) showed that the callus had grown at the original fracture site, and the medial fracture line almost disappeared. CONCLUSION Osteosynthesis remains the first choice of treatment approach for fractures in patients with osteopetrosis, especially peritrochanteric fractures. Preoperative preparation is necessary to avoid risks such as drill bit breakage and iatrogenic fracture during the operation. Moreover, fractures in a patient with osteopetrosis present with a high risk of delayed union and nonunion, which can be potentially cured with PRP + rESWT.

show abstract

“…A population-based cohort study carried out in Minnesota, United States, found that the annual incidence of new ACL injuries, adjusted for sex and age, was 68.6 per 100,000 people [ 7 ]. Although some papers reported orthopaedical surgery as a likely treatment for ADO-2-related fractures [ 8 , 9 ], the treatment of anterior cruciate ligament (ACL) rupture in ADO-2 patients is rarely reported. In addition, there are limited familial genetic analyses as well.…”

Section: Introductionmentioning

confidence: 99%

Anterior cruciate ligament rupture in a patient with Albers-Schonberg disease

Lü

Cheng

Shi

et al. 2022

BMC Musculoskelet Disord

View full text Add to dashboard Cite

Background Osteopetrosis is an uncommon inherited disease marked with elevated bone density and frequent bone fractures owing to flawed osteoclast activity. Autosomal dominant osteopetrosis type 2 (ADO-2), a benign form of osteopetrosis, is also known as Albers-Schonberg disease. Case presentation We report the first successful anterior cruciate ligament (ACL) reconstruction surgery for ACL rupture treatment in a 30-year-old female with ADO-2, who carried a heterozygous missense mutation c.2227C > T (p.Arg743Trp) in exon 23 of the chloride channel 7 (CLCN7) gene. Histopathological analysis of the ruptured ACL sample revealed massive calcium salt deposition in the ligament tissue. A ligament advanced reinforcement system (LARS) artificial ligament was employed in her ACL reconstruction surgery. At her final 16 month’s follow-up, she reported no knee instability symptoms and other complications. The range of motion of the affected knee was good. The side-to-side difference in knee laxity, as evidenced by a KT-1000 arthrometer was 0.9 mm. The Lysholm score improved from 45 before operation to 83 after operation. The Tegner activity score improved from 1 before operation to 4 after operation. Conclusions Our findings further confirmed that the newly identified mutated locus (p.Arg743Trp) may lead to acid secretion disorders at different sites (including calcified ACL in our case). In terms of clinical treatment, ligament reconstruction surgery in patients with Albers-Schonberg disease presents a unique challenge to orthopedic surgeons and requires further preparation and time.

show abstract

Intramedullary nailing for subtrochanteric fracture in autosomal dominant Type II osteopetrosis

Cited by 10 publications

References 13 publications

The Clinical Efficacy of Minimally Invasive Clamp-Assisted Reduction and Open Reduction with Wire Cerclage for Unstable Subtrochanteric Fractures

The Clinical Efficacy of Minimally Invasive Clamp-Assisted Reduction and Open Reduction with Wire Cerclage for Unstable Subtrochanteric Fractures

Treatment for subtrochanteric fracture and subsequent nonunion in an adult patient with osteopetrosis: A case report and review of the literature

Anterior cruciate ligament rupture in a patient with Albers-Schonberg disease

Contact Info

Product

Resources

About