Intramedullary spinal cord metastasis from Ewing sarcoma

Yurtsever, Cagri; Kafadar, Cahit; Sönmez, Güner; Mutlu, Hakan

doi:10.1016/j.spinee.2016.04.006

Cited by 2 publications

(7 citation statements)

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“…The identified cases showed that intramedullary Ewing sarcoma was located mainly in the thoracic and lumbar regions, although cervical and sacral locations were also reported. 4 – 36 The current case had a thoracic intramedullary lesion and a lumbar extramedullary lesion, both causing neural compression and deficits.…”

Section: Discussionmentioning

confidence: 87%

“… 2 The prognosis and survival rate for patients with spinal cord Ewing sarcoma is not well known because of the rarity of the condition; however, based on previous cases ( Table 1 ), the survival rate was 45% to 50% in primary cases and 30% to 35% in recurrent and metastatic cases. 4 – 36 In surviving cases, rehabilitation and physical therapy should be considered part of the treatment program to improve the patient’s neurological status. In the current case, the patient improved markedly after 4 months of physical therapy and rehabilitation.…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…Although metastasis of Ewing sarcoma to the central nervous system (CNS) as well primary CNS disease have been reported previously, involvement of the spinal cord is extremely rare and requires specific management and considerations. 3 To date, only 36 cases of intramedullary Ewing sarcoma have been reported (summarized in Table 1), 4–36 among which there were 31 primary cases 4–11,13,15–17,19–32,34,36 and 5 recurrent and metastatic cases. 12,14,18,33,…”

Section: Introductionmentioning

confidence: 99%

“…3 To date, only 36 cases of intramedullary Ewing sarcoma have been reported (summarized in Table 1), 4–36 among which there were 31 primary cases 4–11,13,15–17,19–32,34,36 and 5 recurrent and metastatic cases. 12,14,18,33,35 Because the number of reported cases of intramedullary Ewing sarcoma is limited, disease management and patient survival data, as well as patient outcomes, remain inconclusive. Previous...…”

Section: Introductionmentioning

confidence: 99%

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Metastatic thoracic and lumbar intramedullary and extramedullary Ewing’s sarcoma: a rare case report and literature review

et al. 2022

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Ewing sarcoma (ES) is a highly aggressive bone and soft tissue tumor that occurs mainly in young children and adolescents and is associated with primary and metastatic disease. Intramedullary ES (either primary or secondary) is rare, and the ideal management remains inconclusive. We herein report intramedullary and extramedullary metastatic ES in a single patient. A 46-year-old woman was referred to our outpatient clinic from the oncology clinic with progressive paraparesis and paresthesia for 1 week prior to presentation. She had developed left clavicular ES 2 years earlier for which surgery and chemoradiotherapy had been performed. At the present evaluation, she was diagnosed with intramedullary thoracic and lumbar extradural masses. Thoracic surgery was performed, and a biopsy of the lesion was obtained. The diagnosis of ES was confirmed histopathologically, and she underwent adjuvant chemotherapy. Her neurological status did not improve after surgery, and she underwent rehabilitation and physical therapy. The lumbar lesion resolved with chemotherapy. Metastasis of ES to the spinal cord, especially intramedullary lesions, is extremely rare, and there is no standard management guideline. However, surgical decompression and adjuvant chemotherapy are the main treatments in these cases.

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