Intramedullary Spinal Cord Tumors in Children

Steinbok, Paul; Cochrane, Douglas; Poskitt, Kenneth J.

doi:10.1016/s1042-3680(18)30636-3

Cited by 65 publications

(19 citation statements)

References 52 publications

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“…Grade 1 is a pilocytic astrocytoma, grade 2 is a low-grade astrocytoma, grade 3 is an anaplastic astrocytoma, and grade 4 is a glioblastoma multiforme. Low-grade tumors tend to be the predominant type (7,9). They are most common in the thoracic region of the spinal cord (10).…”

Section: Types Of Tumorsmentioning

confidence: 99%

Pediatric Spinal Cord Tumors and Masses

Wilson

Oleszek

Clayton

2007

The Journal of Spinal Cord Medicine

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Background/Objective: Spinal cord tumors are a relatively rare diagnosis, accounting for 1% to 10% of all pediatric central nervous system tumors. Understanding the etiology and clinical outcomes of these tumors is therefore very important. This study presents detailed information regarding clinical presentation, histological findings, outcomes, functional assessment, and management of a series of patients with this diagnosis.Method: Retrospective, descriptive study.Subjects: Thirty-five children with a final diagnosis of spinal cord tumor or mass, excluding dysraphism.Results: Neurodevelopmental tumors (dermoid tumors, epidermoid tumors, and teratomas) were the most common tumor type (31%), followed by astrocytomas (29%) and neuroblastomas (14%). Other types included schwannomas, meningiomas, giant cell tumors, extradural cystic masses, leukemic-related masses, and masses related to neurofibromatosis. Mean age at diagnosis was 6.6 years (SD ¼ 5.5 y) and did not vary significantly by tumor type except for children with neuroblastoma (mean ¼ 0.4 y, SD ¼ 0.5 y). More boys (57%) were identified in the series than girls (43%); however, there was no association between tumor type and sex. Presenting complaints of pain were noted in 57% and were localized to the back, neck, or extremities. Extremity weakness was reported as an initial presenting symptom in 46%. Three children had scoliosis as a presenting issue and 14 had gait abnormalities. Regardless of treatment modality, mobility was retained in 83% of children with or without gait aids. Neurogenic bowel and/or bladder were present in 23% of the population.Conclusions: This study corroborates other studies indicating that intramedullary tumors are the predominant form of pediatric spinal cord tumor. This population, however, presented with an unusually large number of developmental tumors, contrary to several published studies. The disparity may be the result of this institution acting as a regional referral center, thus increasing the number of this type of patient. The population is too small to make any other conjecture. The predominance of astrocytomas and neuroblastomas among those patients with poor outcomes and the prevalence of developmental tumors suggest the need for broader investigation. Although, in general, spinal cord tumors are relatively rare, this preliminary study supports the need to further evaluate associations between tumor type, presenting symptoms, treatment, and functional outcome in children with spinal cord tumors.J Spinal Cord Med. 2007;30:S15-S20

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Section: Types Of Tumorsmentioning

confidence: 99%

Pediatric Spinal Cord Tumors and Masses

Wilson

Oleszek

Clayton

2007

The Journal of Spinal Cord Medicine

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“…29 During resection of spinal meningiomas, motor and sensory pathways could be affected separately. 26 Several groups reported postoperative motor deficits despite recording normal intraoperative SSEPs during tumor resection.…”

Section: Neuromonitoring Techniquesmentioning

confidence: 99%

Spinal meningiomas: surgical management and outcome

Gottfried

Gluf

Quiñones‐Hinojosa

et al. 2003

FOC

191

163

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Advances in imaging and surgical technique have improved the treatment of spinal meningiomas; these include magnetic resonance imaging, intraoperative ultrasonography, neuromonitoring, the operative microscope, and ultrasonic cavitation aspirators. This study is a retrospective review of all patients treated at a single institution and with a pathologically confirmed diagnosis of spinal meningioma. Additionally the authors analyze data obtained in 556 patients reported in six large series in the literature, evaluating surgical techniques, results, and functional outcomes. Overall, surgical treatment of spinal meningiomas is associated with favorable outcomes. Spinal meningiomas can be completely resected, are associated with postoperative functional improvement, and the rate of recurrence is low.

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“…Electrophysiological monitoring has become a standard procedure in intramedullary tumor surgery (14). Motor and sensory pathways can be affected independently in both the pre-and postoperative periods (15).…”

Section: Discussionmentioning

confidence: 99%

Spinal Dorsal Meningioma

Kurtoglu¹,

Yavuz²,

Taştekin³

et al. 2014

Turk J Phys Med Rehab

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Meningiomas are usually benign, slow-growing tumors that originate from arachnoid cap cells. Spinal meningiomas represent 12% of all meningiomas. They tend to grow slowly and cause different symptoms, depending on the region affected; therefore, the time between the onset of symptoms and diagnosis is variable. Before the frequent use of magnetic resonance imaging (MRI), some cases with spinal meningiomas were reported to be operated on with a misdiagnosis of lumbar disc herniation or knee disorder. Here, we report a case of a patient who had been operated on with the diagnosis of lumbar spinal stenosis but had complaints of weakness in the legs and difficulty walking. The patient did not improve after the operation. Further investigations after the surgery revealed that the patient had spinal meningioma. Key Words: Meningioma, spinal stenosis, spine tumor Özet Meningiomlar; araknoid hücrelerden köken alan, tipik olarak selim karakterde, yavaş büyüyen tümörlerdir. Tüm meningiomlar içerisinde spinal meningiomlar %12 sıklıkta görülmektedir. Genellikle yavaş büyüme eğiliminde olmaları ve bulundukları bölgeye göre farklı semptom oluşturmaları nedeniyle semptomların başlamasıyla tanı konulması arasında geçen süre değişkendir. Manyetik rezonans (MR) görüntüleme öncesinde bazı spinal meningiomlu olguların lomber disk hernisi veya diz cerrahisi geçirdikleri bildirilmiştir. Burada 67 yaşında uzun süredir bel ağrısı ve alt ekstremitede ilerleyici kas gücü kaybı olan, lomber spinal stenoz tanısıyla opere edildikten sonra dorsal meningiom tanısı alan bir hastayı sunduk. Ameliyat sonrası tarafımıza başvuran hastayı rehabilitasyon amacıyla servisimizde takip ettik.

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Intramedullary Spinal Cord Tumors in Children

Cited by 65 publications

References 52 publications

Pediatric Spinal Cord Tumors and Masses

Pediatric Spinal Cord Tumors and Masses

Spinal meningiomas: surgical management and outcome

Spinal Dorsal Meningioma

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