Intramedullary spinal tumor-like lesions

Maj, Edyta; Wójtowicz, Katarzyna; Aleksandra,; Podlecka-Piȩtowska,; Prokopienko, Marek; Marchel, Andrzej; Rowiński, Olgierd; Bekiesińska‐Figatowska, Monika

doi:10.1177/0284185118809540

Cited by 8 publications

(4 citation statements)

References 51 publications

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“…e tibia has an irregular characteristic, which is the body's maximum flat bone, which is a large number of bone tumors, with the proportion of metastasis than being relatively high, and other bone marrow tumors, bone malignant lymphoma [7][8][9]. Clinical data show that the incidence of ilibular disease in the primary malignant bone tumor is about 9.6%, of which the patient is high in chondrosatoma is high, and it is an osteosarcoma, and Juventi meat [10][11][12].…”

Section: Discussionmentioning

confidence: 99%

Imaging Diagnosis of Primary Solitary Bone Neoplasts and Its Comparison with Tumor-like Lesions

Wei

Zheng

Tang

2022

Evidence-Based Complementary and Alternative Medicine

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Objective. To explore the imaging diagnostic value of primary solitary bone tumor and tumor-like lesion of iliac crest. Methods. A total of 156 patients with primary solitary bone tumors and tumor-like lesions of the iliac bone treated in our hospital were selected, and the patients were diagnosed by X-ray, CT, and MRI. Sexual analysis of single diagnostic and combined diagnostic value was carried out. Results. Round high-density shadow, soft tissue mass shadow, soft tissue mass, right intestinal tube, and bladder obvious pressure were observed. The detection rates of giant cell tumor of bone, myeloma, osteochondroma, chondroma, eosinophilic granuloma, osteosarcoma, fibrous dysplasia, and Hodgkin lymphoma were 34.6%, 12.8%, 11.5%, 10.3%, 7.7%, 6.4%, 3.8%, and 2.6%, and the differences were statistically significant (P < 005); X-ray, CT, MR single diagnostic comparison, three methods joint diagnostic missed diagnosis rate and misdiagnosis rate, higher detection rate ( P < 0.05 ); combined with X-ray, CT, MR single diagnosis, three methods joint diagnosis sensitivity, specificity, accuracy, statistical significance ( P < 0.05 ); comparison with X-ray, CT, MR single diagnosis, three methods jointly diagnosed positive predictive value, negative predictive value higher, difference statistics significance ( P < 0.05 ); there is a significant difference in the near-end, backbone, and distal detection rate of different bone tumors and tumor lesions, including the humerus and tibia. There is a statistical significance of the detection rate, and the difference is P < 0.05 . Conclusion. X-ray plays an important role in the diagnosis of primary solitary bone tumor and tumor-like lesion of iliac crest and is the first choice in clinical diagnosis. In the diagnosis of tumor disease, range, and soft tissue mass, MRI and CT diagnostic value can provide effective theoretical basis for patient clinical treatment. Therefore, the appropriate diagnostic method should be selected according to the specific situation of the patient, so that the efficiency of the clinical feature is improved.

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Section: Discussionmentioning

confidence: 99%

Imaging Diagnosis of Primary Solitary Bone Neoplasts and Its Comparison with Tumor-like Lesions

Wei

Zheng

Tang

2022

Evidence-Based Complementary and Alternative Medicine

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“…30 Similar involvement of the dorsal columns is seen in other nutritional deficiencies such as copper and vitamin E. Corticospinal tract involvement is suggestive of hepatic myelopathy and amyotrophic lateral sclerosis, 31 while anterior horn involvement is more frequently associated with niacin deficiency. 32 Given the imaging overlap of these various entities, differentiation among these myelopathies relies primarily on clinical history and laboratory work-up. Sarcoidosis is a granulomatous disorder with multisystem involvement that rarely includes myelopathy.…”

Section: Infectionmentioning

confidence: 99%

“…33 Postradiation myelopathy is a rare complication that is most commonly seen 6 to 24 months after radiation therapy. 32 The findings include abnormal T2 signal involving the central two-thirds of the cord at levels within the radiation field; fatty marrow changes are often seen at these levels, as well (►Fig. 13).…”

Section: Infectionmentioning

confidence: 99%

Imaging Considerations in Spinal Cord Evaluation

2021

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Multiple diverse pathologies result in the clinical presentation of myelopathy. The preferred way to image the spinal cord depends on clinical history, anatomic site of interest, and patient issues limiting certain imaging modalities. This radiology-focused article discusses pertinent physiological considerations, reviews basic and newer imaging techniques, and examines several distinct disease entities in order to highlight the key role of imaging in the work-up of myelopathy.

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“…Their clinical symptoms, such as local pain, limb weakness, sensory deficit, and sphincter dysfunction, are more closely related to the lesion location rather than its specific pathology (16)(17)(18)(19). As for spinal cord DMGs, their imaging features exhibit substantial overlap with other neoplasms or tumor-like lesions, such as ependymomas (EPNs) and demyelinating disorders (18,20,21), further complicating diagnosis. Yet, few researchers have been dedicated to addressing this diagnostic challenge.…”

Section: Introductionmentioning

confidence: 99%

Distinct MRI characteristics of spinal cord diffuse midline glioma, H3 K27-altered in comparison to spinal cord glioma without H3 K27-alteration and demyelination disorder

Ying,

Liu,

et al. 2023

Acta Radiol

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Background An applicable magnetic resonance imaging (MRI) biomarker for diffuse midline glioma (DMG), H3 K27-altered of the spinal cord is important for non-invasive diagnosis. Purpose To evaluate the efficacy of conventional MRI (cMRI) in distinguishing between DMGs, H3 K27-altered, gliomas without H3 K27-alteration, and demyelinating lesions in the spinal cord. Material and Methods Between January 2017 and February 2023, patients with pathology-confirmed spinal cord gliomas (including ependymomas) with definite H3 K27 status and demyelinating diseases diagnosed by recognized criteria were recruited as the training set for this retrospective study. Morphologic parameter assessment was performed by two neuroradiologists on T1-weighted, T2-weighted, and contrast-enhanced T1-weighted imaging. Variables with high inter- and intra-observer agreement were included in univariable correlation analysis and multivariable logistic regression. The performance of the final model was verified by internal and external testing sets. Results The training cohort included 21 patients with DMGs (13 men; mean age = 34.57 ± 13.489 years), 21 with wild-type gliomas (10 men; mean age = 46.76 ± 17.017 years), and 20 with demyelinating diseases (5 men; mean age = 49.50 ± 18.872 years). A significant difference was observed in MRI features, including cyst(s), hemorrhage, pial thickening with enhancement, and the maximum anteroposterior diameter of the spinal cord. The prediction model, integrating age, age2, and morphological characteristics, demonstrated good performance in the internal and external testing cohort (accuracy: 0.810 and 0.800, specificity: 0.810 and 0.720, sensitivity: 0.872 and 0.849, respectively). Conclusion Based on cMRI, we developed a model with good performance for differentiating among DMGs, H3 K27-altered, wild-type glioma, and demyelinating lesions in the spinal cord.

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Intramedullary spinal tumor-like lesions

Cited by 8 publications

References 51 publications

Imaging Diagnosis of Primary Solitary Bone Neoplasts and Its Comparison with Tumor-like Lesions

Imaging Diagnosis of Primary Solitary Bone Neoplasts and Its Comparison with Tumor-like Lesions

Imaging Considerations in Spinal Cord Evaluation

Distinct MRI characteristics of spinal cord diffuse midline glioma, H3 K27-altered in comparison to spinal cord glioma without H3 K27-alteration and demyelination disorder

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