“…Likewise, more rare causes, such as a spontaneous intramural duodenal hematoma as the manifestation of Noonan syndrome are possible [2]. In adults, trauma [3] and biopsies [4] are also described as causes of an IDH, but various other reasons and risk factors are mentioned, such as percutaneous endoscopic gastrostomy [5], endoscopic injection therapy of a bleeding ulcer [6,7], an anticoagulating therapy [8], coagulopathy (e.g., Willebrand disease) [9] or an IDH as a complication of alcohol-induced pancreatitis [10,11]. In this article, we report a rare case of a large intramural duodenal hematoma following elective endoscopic duodenal biopsy to exclude celiac disease in a previously healthy 6-year-old boy.…”