Intramuscular myxoma of the paraspinal muscles: A case report and systematic review of the literature

Abstract

Abstract. Intramuscular myxoma (IM) is a rare mesenchymal tumor of the head and neck region. The current study reports a case of a 45-year-old man who presented with a painless neck mass. Imaging showed involvement of the levator scapulae and scalene muscles. Core needle biopsy was consistent with intramuscular myxoma. Surgical excision was performed and follow-up for 30 months showed no recurrence. The present study includes a systematic review of head and neck IMs, with a summary of the clinical and demographic param eters of all reported cases in the head and neck region. Surgery was curative in 28 of the 29 published cases, as well as in the current case (96.7%), with the lone recurrent tumor cured following re-resection. Females constituted 57% of the cases and the mean age was 49.7±20.4 years. Although uncommon, IM should be considered in the differential diagnosis of deep neck masses, and surgical excision is the treatment of choice with a low risk of recurrence.

Intramuscular Myxoma in the Supinator Muscle with Transient Postoperative Posterior Interosseous Nerve Palsy: A Case Report

“…Intramuscular myxomas arise from skeletal muscles, and they were described as a distinct subtype of myxomas [ 6 ]. Intramuscular myxomas usually occur between the fourth and seventh decades of life and more frequently in women [ 7 ]. Intramuscular myxomas usually manifest as a single mass; however, several intramuscular myxomas have manifested with fibrous dysplasia as part of Mazabraud’s syndrome [ 8 ].…”

An Interesting Case of Intramuscular Myxoma with Scapular Bone Lysis

“…Intramuscular myxomas are localized in skeletal muscles; they represent a distinct subtype of myxomas and have been described for the first time in 1965 by Enzinger [ 1 ], constituting only 17% of all soft tissue myxoma cases in his study. They occur more frequently in females and usually affect patients between 40 and 70 years of age [ 2 ].…”

“…The etiology of myxomas remains elusive. Some authors suggested a traumatic origin [ 2 ]. It is also possible that growth of polysaccharide-producing cells is implicated in the neoplastic process [ 1 , 15 ].…”

“…Myxoma is a rare benign primitive tumor of the mesenchyme [ 1 ]; it presents itself like an unpainful, slow-growing mass. It is even more rare at the skeletal muscle level [ 2 ] and is named in this case “intramuscular myxoma.” We describe here an exceptional case of intramuscular myxoma in the deltoid, which has the particularity to lyse the surrounding scapular bone. This bone lysis is almost unique; indeed, only 7 cases have been reported since the fifties, but never at the shoulder level.…”

A case of a myxoma within the obturator externus muscle

“…Other than intramuscular, other subtypes of myxomas exist such as juxta-articular myxoma, aggressive angiomyxoma, superficial angiomyxoma, and nerve sheath myxoma [3]. IM usually occur in patients between the fourth and sixth decade and have female predominance [4]. The clinical presentation is of as slow growing painless mass, nonetheless the majority of the patients are asymptomatic.…”