Intramuscular myxoma of the thigh: A case report

Abstract

Intramuscular Myxomas are rare benign soft tissue tumors which usually occur between the ages 40 and 70 years and are more common among females. A thorough history and examination can help with diagnosis and it can be confirmed via histological examination. A 40-year-old female presented with a swelling in the medial aspect of right thigh which measured about 5 × 5 cm. Ultrasound, magnetic resonance imaging, and histopathology examination confirmed the diagnosis and a complete surgical resection was performed to remove the mass. Intramuscular myxoma should be included in differential diagnosis of sarcomas, hemangioma, desmoid tumor, clear cell sarcoma, and lipomas. Magnetic resonance imaging should be the investigation of choice, and histopathology remains the gold standard of investigation. Complete surgical excision with negative margins is the treatment of choice.

The Clinical, Radiological, and Histopathological Characteristics of Intramuscular Myxoma: A Case Report

“…Typically described as lesions with low cellular density and reduced vascularity, with significant accumulation of extracellular myxoid matrix, these tumors can exhibit increased cellularity and vascularity with intramuscular localization, which can sometimes lead to a misdiagnosis of sarcoma. Patients usually report swelling, which occurs in regions rich in large muscles such as thighs, shoulders, arms, and buttocks [1].…”

“…Diagnosis is based on history, a thorough physical examination, imaging data, and most importantly, histology which provides certainty. History reveals the onset of swelling in areas with large muscles: thighs, shoulders, arms, and buttocks [1]. Some authors report overweight in these patients without considering it a determining risk factor [2,7].…”

“…Intramuscular myxomas (IMM) are rare benign tumors affecting the soft tissue of mesenchymal origin [1]. They were first described in 1965 by Enzinger [2].…”

“…They were first described in 1965 by Enzinger [2]. Their incidence varies between 0.1 and 0.3 per 100,000 individuals and is often seen in females aged between 40 and 70 years [1]. The most common location is in the muscles of the thigh, with less frequent occurrences in the shoulder, buttocks, leg, and arm [3,4].…”