Intranasal and Serum Gentamicin Concentration: Comparison of Three Topical Administration Protocols in Dogs
Tom Biénès,
Aurélie Lyssens,
Hélène Machiels
et al.
Abstract:Antimicrobials’ topical administration efficacy has not been assessed in dogs with upper respiratory tract disease. The aim was to compare the concentration of gentamicin in nasal lavage fluid (NALF) and in serum after three topical protocols. This was a prospective crossover study of ten healthy dogs. Gentamicin was nebulized for a duration of 1 week, twice a day, for 10 min in the first protocol (10-min protocol) and for 3 min in the second protocol (3-min protocol), while the third protocol consisted of the… Show more
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