Intranasal lidocaine for the treatment of migraine headache: A randomised, controlled trial

We strongly recommend the use of prochlorperazine based on a high level of evidence, lysine acetylsalicylic acid, metoclopramide and sumatriptan, based on a moderate level of evidence, and ketorolac, based on a low level of evidence. We weakly recommend the use of chlorpromazine based on a moderate level of evidence, and ergotamine, dihydroergotamine, lidocaine intranasal and meperidine, based on a low level of evidence. We found evidence to recommend strongly against the use of dexamethasone, based on a moderate level of evidence, and granisetron, haloperidol and trimethobenzamide based on a low level of evidence. Based on moderate-quality evidence, we recommend weakly against the use of acetaminophen and magnesium sulfate. Based on low-quality evidence, we recommend weakly against the use of diclofenac, droperidol, lidocaine intravenous, lysine clonixinate, morphine, propofol, sodium valproate and tramadol.

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Canadian Headache Society systematic review and recommendations on the treatment of migraine pain in emergency settings

Orr

et al. 2014

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Intranasal lidocaine for the treatment of migraine headache: A randomised, controlled trial

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Canadian Headache Society systematic review and recommendations on the treatment of migraine pain in emergency settings

Canadian Headache Society systematic review and recommendations on the treatment of migraine pain in emergency settings

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