Background
The saddle shape of the normal mitral annulus has been quantitatively described by several groups. There is strong evidence that this shape is important to valve function. A more complete understanding of regional annular geometry in diseased valves may provide a more educated approach to annuloplasty ring selection and design. We hypothesized that mitral annular shape is markedly distorted in patients with diseased valves.
Methods
Real-time 3-dimensional echocardiography was performed in patients with normal mitral valves (n=20), ischemic mitral regurgitation (IMR, n=10) and myxomatous mitral regurgitation (MMR, n=20). Thirty-six annular points were defined to generate a 3D model of the annulus. Regional annular parameters were measured from these renderings. Left ventricular inner diameter (LVIDd) was obtained from 2D echocardiographic images.
Results
Annular geometry was significantly different between the three groups. The annuli were larger in the MMR and the IMR groups. The annular enlargement was greater and more pervasive in the MMR. Both diseases were associated with annular flattening though the regional distribution of that flattening was different between groups. LVIDd was increased in both groups. However, relative to the LVIDd, the annulus was disproportionately dilated in the MMR group.
Conclusion
Patients with MMR and IMR have enlarged and flattened annuli. In the case of MMR, annular distortions may be the driving factor leading to valve incompetence. These data suggest that the goal of annuloplasty should be the restoration of normal annular saddle shape and that the use of flexible, partial and flat rings may be ill advised.