Intraoperative Blood Salvage in Penetrating Abdominal Trauma: a Randomised, Controlled Trial

Bowley, Douglas M.; Barker, Philip; Boffard, Kenneth D.

doi:10.1007/s00268-005-0466-2

Cited by 86 publications

(110 citation statements)

References 32 publications

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“…In a series of 152 penetrating abdominal injuries there was no difference in wound infection rates between patients receiving allogeneic or cell saved blood, and no correlation between organisms grown from the cell saved blood and those causing postoperative pneumonias, bacteraemias or urinary tract infections [24]. This has been confirmed in a recent prospective, randomised controlled trial of penetrating abdominal injuries in which the use of cell salvage at laparotomy led to a significant reduction in allogeneic blood usage with no discernable effect on rates of postoperative infection or mortality [25]. Most surgeons and anaesthetists still avoid salvage from grossly contaminated fields, but procedures involving bowel resection now commonly use cell salvage for at least part of the procedure.…”

Section: Discussionmentioning

confidence: 80%

Use of a leucocyte filter to remove tumour cells from intra‐operative cell salvage blood

Catling¹,

Williams²,

Freites³

et al. 2008

Anaesthesia

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SummaryThe intra-operative blood loss of 50 consecutive gynae-oncology patients undergoing surgery for endometrial, cervical or ovarian cancer was cell salvaged and filtered. In each case blood samples were taken from the effluent tumour vein, a central venous line, the cell saver reservoir, the cell salvage re-transfusion bag after processing but before filtration and from the cell salvage re-transfusion bag after processing and filtration. Samples were examined using immunohistochemical monoclonal antibody markers for epithelial cell lines. Viable, nucleated malignant cells were detected in 2 ⁄ 50 central venous samples, 34 ⁄ 50 reservoir samples and 31 ⁄ 50 unfiltered cell salvaged samples. After passage through a Pall RS leucocyte depletion filter no remaining viable, nucleated malignant cells were detected in any sample. The clinical risks of cell salvage in these circumstances should be reviewed in the light of the risks of allogeneic blood transfusion.

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Section: Discussionmentioning

confidence: 80%

Use of a leucocyte filter to remove tumour cells from intra‐operative cell salvage blood

Catling¹,

Williams²,

Freites³

et al. 2008

Anaesthesia

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“…It has been demonstrated that bacteria are not completely removed by centrifugation and washing (5-21% subsequently present) (Boudraux et al 1983, Faugth et al 1998. As described in the trauma study (Bowley et al 2006), in emergency cases, autotransfusion can be life-saving without causing harm to the patient. A few other case-reports confirm that prophylactic intravenous antibiotic therapy or addition of antibiotics to the anticoagulant solution could prevent bacteraemia or sepsis (Faught et al 1998, Wollinsky et al 1997).…”

Section: Bacterial Contaminationmentioning

confidence: 99%

“…In this field, just one randomised study has been published, subjects experiencing abdominal trauma in combination with bowel perforations (n = 44; Bowley et al 2006). Bowel perforation is generally considered a contraindication to autotransfusion.…”

Section: Autotransfusion In Traumatologymentioning

confidence: 99%

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Autotransfusion: Therapeutic Principles, Efficacy and Risks

Gemert¹

2012

Blood Transfusion in Clinical Practice

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“…Infusion devices, gravity or electronic, may be used for the administration of blood and blood components in situation where rapid infusion seems necessarily (Grade 2C) [56,57]. However, a close observation is needed to avoid risk of hemolysis that can be endured by rapid infusion or malfunction of such devices.…”

Section: Fresh Frozenmentioning

confidence: 99%

Literature Review for Management of Massive Hemorrhage

Aljedani¹

2016

HTIJ

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Introduction: Management of massive hemorrhage has been advanced in the last decade and the survival rate of patients who suffered from massive hemorrhage had been improved. Evidence-based recommendations are required to guide the management of such situations, which when implemented may improve patient outcomes.Methods: Data were collected by review for articles, clinical trials and guidelines. Searches were restricted to articles written in English that were published during the period January 1988 through August 2015. The key recommendations in this article were made based on The Grading of Recommendations Assessment, Development and Evaluation (GRADE) system. Discussion: Over the recent years, massive hemorrhage is been managed by blood components transfusion and surgical or radiological intervention as applicable. With the advanced laboratory assays and point of care tests, surgical and radiological intervention methods and the availability of factor concentrates preparations, the survival of patients with massive hemorrhage has been improved significantly. Conclusion:This article discusses the available evidences and recommendations regarding management of patients with massive hemorrhage.

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Intraoperative Blood Salvage in Penetrating Abdominal Trauma: a Randomised, Controlled Trial

Abstract: In this randomised, controlled trial for patients with penetrating abdominal injuries, IBS led to a significant reduction in allogeneic blood usage with no discernable effect on rates of postoperative infection or mortality.

Cited by 86 publications

References 32 publications

Use of a leucocyte filter to remove tumour cells from intra‐operative cell salvage blood

Use of a leucocyte filter to remove tumour cells from intra‐operative cell salvage blood

Autotransfusion: Therapeutic Principles, Efficacy and Risks

Literature Review for Management of Massive Hemorrhage

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