Intraoperative Hypoxia and Hypotension Caused by Gastrografin-induced Hypovolemia

Maneksha, Farrokh R.; Betta, JoAnn; Zawin, Marlene; Poppers, Paul J.

doi:10.1097/00000542-198410000-00015

Cited by 10 publications

(6 citation statements)

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“…Many earlier studies were concerned that the high osmolality of Gastrografin ® could cause tissue dehydration and epithelial cell damage [19][20][21][22], and therefore the possibility of bowel perforation always existed in water-soluble contrast enemas [1,3,16,23]. However in this study, the procedure-related bowel perforation itself developed only in 3 cases (9.1% on per-patient basis), and the possibility of perforation seems to be relatively low as compared with the previous reports of spontaneous perforation rate in untreated MO (about 30%) [2,24].…”

Section: Discussionmentioning

confidence: 99%

Ultrasound-guided contrast enema for meconium obstruction in very low birth weight infants: Factors that affect treatment success

Cho

Cheon

Choi

et al. 2015

European Journal of Radiology

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Section: Discussionmentioning

confidence: 99%

Ultrasound-guided contrast enema for meconium obstruction in very low birth weight infants: Factors that affect treatment success

Cho

Cheon

Choi

et al. 2015

European Journal of Radiology

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“…These factors, along with greater safety in animals with suspected intestinal perforation or subsequent surgery, make Gastrografin® an appropriate choice for contrast radiography of the gastrointestinal tract of red‐eared slider turtles. However, a hyperosmolar contrast medium may lead to hypovolemia and dehydration due to fluid loss from the bowel 6,11,12,14,15 . This is especially true of small animals, neonates, and critically ill patients 6,12,14,15 …”

Section: Introductionmentioning

confidence: 99%

“…However, a hyperosmolar contrast medium may lead to hypovolemia and dehydration due to fluid loss from the bowel 6,11,12,14,15 . This is especially true of small animals, neonates, and critically ill patients 6,12,14,15 …”

Section: Introductionmentioning

confidence: 99%

“…6,11,12,14,15 This is especially true of small animals, neonates, and critically ill patients. 6,12,14,15 General recommendations for gastrointestinal contrast studies in turtles have focused on larger sea turtles 6 and herbivorous terrestrial chelonians [8][9][10][11] but a detailed comparison of gastrointestinal contrast radiography in smaller semi-aquatic turtles is lacking. Our primary objective was to compare Gastrografin s with barium sulfate in regard to ease of administration, transit time, and image quality.…”

Section: Introductionmentioning

confidence: 99%

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COMPARISON OF GASTROGRAFIN TO BARIUM SULFATE AS A GASTROINTESTINAL CONTRAST AGENT IN RED‐EARED SLIDER TURTLES (TRACHEMYS SCRIPTA ELEGANS)

Long

Page

Howard

et al. 2010

Vet Radiology Ultrasound

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Red-eared slider turtles (Trachemys scripta elegans) commonly develop intestinal obstruction. The gastrointestinal transit time in turtles tends to be longer than in other animals, making a rapid diagnosis of obstruction difficult. Fifteen red-eared sliders were given either Gastrografin or 30% w/v barium sulfate orally to compare ease of administration, transit time, and image quality. Each contrast medium was easy to administer but barium sulfate had to be administered more slowly (mean = 40s) than Gastrografin (mean = 20s) to prevent regurgitation. The mean transit and emptying time of Gastrografin was at least 9 h faster than barium sulfate at all time points except gastric transit. Both contrast media had a smooth, uniform appearance that outlined the mucosa with well-defined margins within the stomach and proximal small intestine. Dilution of Gastrografin occurred as it progressed through the intestines, resulting in decreased opacity in the distal small intestine and colon. Pre-administration packed cell volume and total serum protein levels of four turtles receiving Gastrografin were compared with levels at 24-, 96-, and 168-hours postadministration as well as to four control turtles not receiving contrast medium. Packed cell volume and total serum protein levels did not significantly differ among the Gastrografin and control group. From a clinical perspective, administration of Gastrografin allows for quicker results with only minor hematologic changes in red-eared sliders, but visualization of this contrast medium in the lower gastrointestinal tract may be insufficient for an accurate diagnosis.

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“…This procedure has also been used for the treatment of MO. However, various complications related to gastrographin enemas can occur [8,9] partly due to their hyperosmolarity. This procedure is usually performed in a radiology suite to allow real-time observation under a fluoroscope to prevent intestinal perforation and to confirm that the agent reaches its target site.…”

Section: Introductionmentioning

confidence: 99%

Iopamidol enema treatment for meconium obstruction of prematurity in extremely low-birth weight infants: a safe and effective method

et al. 2009

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Intraoperative Hypoxia and Hypotension Caused by Gastrografin-induced Hypovolemia

Cited by 10 publications

References 0 publications

Ultrasound-guided contrast enema for meconium obstruction in very low birth weight infants: Factors that affect treatment success

Ultrasound-guided contrast enema for meconium obstruction in very low birth weight infants: Factors that affect treatment success

COMPARISON OF GASTROGRAFIN TO BARIUM SULFATE AS A GASTROINTESTINAL CONTRAST AGENT IN RED‐EARED SLIDER TURTLES (TRACHEMYS SCRIPTA ELEGANS)

Iopamidol enema treatment for meconium obstruction of prematurity in extremely low-birth weight infants: a safe and effective method

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