Intraoperative intravenous lidocaine reduces hospital length of stay following open gastrectomy for stomach cancer in men

Transversus Abdominis Plane Block to Ameliorate Postoperative Pain Outcomes After Laparoscopic Surgery

“…Because the performance of TAP block can be time-consuming and it requires a certain degree of expertise, other less invasive multimodal strategies such as perioperative systemic lidocaine, magnesium, and dexamethasone may be valuable alternatives to TAP block. [46][47][48] Our current meta-analysis has substantial differences from previous quantitative systematic reviews. 8,9,49 First, to the best of our knowledge, we included a larger number of trials and subjects in our analysis than previous authors.…”

Systemic lidocaine in surgical procedures

“…lidocaine was found in relation to bowel motility in the 2012 study by Kang et al [23]. The authors examined patients who had undergone gastrectomy and only found nonsignificant differences between the lidocaine group and the control group.…”

“…Harvey et al [21] came to similar conclusions in a study published in 2009, although it only included 22 patients receiving elective bowel surgery. In their 2012 study, Kang et al [23] also investigated the time of discharge as the primary end point. Forty-eight patients undergoing gastrectomy were randomly assigned to an i.v.…”

Intravenous lidocaine to treat postoperative pain

“…In breast cancer surgeries, authors have observed that this perioperative lidocaine infusion regimen has decreased the area of hyperalgesia as compared to placebo, but postoperative analgesia at rest was superior only in the 4 th postoperative hour 42 . Another author using the same lidocaine dose, however limiting end of infusion to skin closure in male patients submitted to subtotal gastrectomy, has observed no difference in analgesia in the first 3 postoperative days as compared to placebo 43 . Based on the above, some questions arise: which is the ideal dose to obtain postoperative analgesia?…”