Intraoperative optical coherence tomography: past, present, and future

Abstract

To provide an overview of the current state of intraoperative optical coherence tomography (OCT). Literature review of studies pertaining to intraoperative OCT examining both the technology aspects of the imaging platform and the current evidence for patient care. Over the last several years, there have been significant advances in integrative technology for intraoperative OCT. This has resulted in the development of multiple microscopeintegrated systems and a rapidly expanding field of image-guided surgical care. Multiple studies have demonstrated the potential role for intraoperative OCT in facilitating surgeon understanding of the surgical environment, tissue configuration, and overall changes to anatomy. In fact, the PIONEER and DISCOVER studies, both demonstrated a potential significant percentage of cases that intraoperative OCT alters surgical decision-making in both anterior and posterior segment surgery. Current areas of exploration and development include OCT-compatible instrumentation, automated tracking, intraoperative OCT software platforms, and surgeon feedback/visualization platforms. Intraoperative OCT is an emerging technology that holds promise for enhancing the surgical care of both anterior segment and posterior segment conditions. Hurdles remain for adoption and widespread utilization, including cost, optimized feedback platforms, and more definitive value for individualized surgical care with image guidance.

Optical coherence tomography: A guide to interpretation of common macular diseases

“…Newer developments with the technology include intraoperative OCT,[ 106 107 ] ultra-wide field OCT,[ 108 ] OCT Angiography and its newer algorithms including optical microangiography, speckle variance, phase variance, split-spectrum amplitude-decorrelation angiography, and correlation mapping,[ 109 ] and adaptive optics OCT.[ 110 ] These would further enhance understanding of both anatomical and functional aspects of retinal pathology.…”

Subretinal surgery: functional and histological consequences of entry into the subretinal space

“…In the recent progress of intraocular surgery, two main factors have played a significant role. The first is better perioperative intraocular visualization with improved surgical microscopes and ocular coherence tomography (OCT) (Ehlers ), and the second is a significant decrease in instrument size and thereby minimal inflicted damage (Mohamed et al. ).…”

Intraoperative optische Kohärenztomografie bei der tiefen anterioren lamellären Keratoplastik

“…Vor allem bei reduziertem Einblick in die Augenvorderkammer ist die intraoperative OCT dem reinen Mikroskop deutlich überlegen. Auch die posteriore lamelläre Transplantationschirurgie (DMEK), die Boston-Keratoprothese, die Kanaloplastik lassen sich mittels OCT intraoperativ in komplizierten Ausgangssituationen überwachen [17][18][19][20][21][22]. Dabei konnte z.…”