Intraoral angiosarcoma: Treatment with a brachytherapy prosthesis

Abstract

Angiosarcomas are rare, malignant neoplasms of vascular origin that account for less than 1% of all soft tissue tumors. Angiosarcomas of the oral cavity are especially rare, and brachytherapy may be prescribed as a localized treatment to manage these malignancies. Intraoral brachytherapy requires collaboration between the radiation oncologist and a dental professional for the fabrication of the brachytherapy delivery prosthesis. The present clinical report describes an intraoral angiosarcoma and the fabrication of an intraoral brachytherapy prosthesis to manage this malignancy.

High‐dose‐rate remote brachytherapy for metachronous second primary carcinoma of soft palate by iridium 192 isotope in an afterload surface mold

“…This minimized the radiation scatter to the uninvolved tissue and consistent dosimetry to the tissues as per plan. 10,11 This also allowed for fractionation of dose with single dosimetric calculations. 13 Fractionation of dose enables adequate therapeutic sode to be delivered with minimal adverse effect.…”

“…Several methods of fabrication of mold for brachytherapy have been documented. [7][8][9][10][11][12][13] PMMA based molds frequently carry wrought metal clasps which create disturbance in computer tomography (CT) scan during dosimetry. Gamma radiation has also been implicated to induce metal ion release and free radical formation with metal clasps.…”

Individual multi-catheter mould technique in high-dose-rate brachytherapy – personalized approach in treating multifocal angiosarcoma of the face

“…Efficacy and safety of the surface brachytherapy in the skin lesions management, especially non-melanoma skin cancer, has been well documented. Different techniques and applicators can be used to deliver a dose to skin [16,17,24,25]. Stepping source ( 192 Ir) has an optimal dose profile to deliver the dose to the skin surface efficiently with excellent and good cosmetic outcomes [24].…”

A modified technique for fabrication of custom-made afterload brachytherapy appliance

“…In previous studies, the mold was prepared with the help of flexible nylon tubes,[14] with either steel wires[6] or dummy seeds positioned within the tubes and sealed with auto polymerizing acrylic resin and in some studies, brachytherapy catheters[1516] were also used; however, these catheters are more stiffer and are not flexible enough to get adapted easily without wrenching to treat intraoral carcinomas.…”