Intraoral corroboration of systemic plasma-cell myeloma

Barr, Gary S.; Zweig, Barry; Itkin, Allen B.

doi:10.1016/0030-4220(76)90027-x

Cited by 11 publications

(2 citation statements)

References 10 publications

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“…Most of the reported bone lesions were associated to clinical sweeling, 1 , 8 , 9 , 12 , 13 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 31 , 32 , 33 , 34 which may be explained by tumor expansion with neoplastic plasma cell activity in the bone. 15 It may be assumed that swelling is a late stage of jaw lesions, after the tumor has expanded.…”

Section: Discussionmentioning

confidence: 99%

“… 4 Commonly, bone lesions may be represented by diffuse or localized osteolytic lesions, named plasmacytomas, or by a ‘punched-out’ pattern. 1 The maxillary and mandibular bones may be affected by these lesions, 1 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 and nearly 35% of patients diagnosed with symptomatic MM present lesions in the jaws. 28 …”

Section: Introductionmentioning

confidence: 99%

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Can dentists detect multiple myeloma through oral manifestations?

Almeida

Cavalcanti

Freitas

et al. 2018

Hematology, Transfusion and Cell Therapy

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ObjectiveTo review published data on oral manifestations of multiple myeloma.MethodsAn electronic database search was performed of articles published from 1971 to November 2016 in order to identify studies that reported oral manifestations of patients with multiple myeloma. Case reports and case series with oral manifestations of multiple myeloma in English were included in the study. An additional search was performed of the references of the selected articles.ResultsThirty-seven articles that reported 81 patients with oral manifestations of multiple myeloma were selected: 30 case reports (82%) and seven case series (18%). The most common clinical features in the dental cavity were swelling (65.4%), bone pain (33.3%), paresthesia (27.1%) and amyloidosis lesions (11.1%). Osteolytic lesions detected on imaging exams were reported in the majority of the patients (90.1%) as plasmacytomas or ‘punched-out’ lesions.ConclusionsSwelling and osteolytic lesions represent the most common clinical and radiographic signs of the jaws relating to multiple myeloma, respectively.

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