Intraoral minor salivary gland tumors: A demographic and histologic study of 200 cases.

Abstract

In a demographic and histologic study of 200 intraoral minor salivary gland tumors seen in Japan (Nagasaki and Miyagi prefectures), 127 cases (63.5%) were classified as benign, comprising 124 pleomorphic adenomas and 3 monomorphic adenomas. The other 73 cases (36.5%) were malignant tumors, represented by 33 adenoid cystic carcinomas, 16 mucoepidermoid carcinomas, 10 carcinoma in pleomorphic adenomas, 6 acinic cell carcinomas, 5 adenocarcinomas, one polymorphous low-grade adenocarcinoma, one undifferentiated carcinoma and one clear cell carcinoma. There was an overall female preponderance (1.78/1). The mean age for females was 47.2 years and for males was 50.6 years. The mean age for patients with malignant tumors was 10 years greater than for patients with benign tumors and was statistically significant. The palate was the most common site for intraoral minor salivary gland tumors followed by the lip and buccal mucosa. These three sites accounted for 83° of all cases. Tumors arising in these three sites were predominantly benign. In contrast, those located in the gingiva, floor of the mouth and tongue were predominantly malignant. The results of this study were compared with other recent studies.-minor salivary gland ; tumors ; histology ; age and sex ; Japanese Neoplasms of minor salivary gland origin occur much less commonly than those arising from major salivary glands (Gorlin and Chaudhry 1957;Richardson et al. 1975;Main et al. 1976;Shrikhande and Talvalker 1978;DelBalso 1979;Perzin and LiVolsi 1979;Brocheriou et al. 1980;Eveson and Cawson 1985b). In spite of their relative infrequency in terms of the total number of cases accessioned in most oral or hospital surgical pathology services (Regezi et al.

Malignant minor salivary gland tumors: a retrospective study of 27 cases

“…The main age group was found between 60-79 years; that is also supported in other studies [11,12]. Also, the present study shows the palate as the predominant location (62.9% in the hard and soft palate), a finding comparable to those of other current studies [4,5,10]. Concerning recurrence, only a very few studies are available because of late metastasis, older age of patients, and lower incidence of these tumors.…”

“…Most reports describe a female predominance in minor salivary gland tumors [4,5] similar to the proportion in the present study, which shows female to male as 7:6. The main age group was found between 60-79 years; that is also supported in other studies [11,12].…”

“…In several studies, adenoid cystic carcinoma has been shown as being most common [4][5][6], with several other studies showing, on the other hand, that mucoepidermoid carcinoma is the most common (Table 5) [2,[7][8][9][10]. Some authors describe the tumor distribution pattern as varying by country.…”

Intraoral minor salivary gland tumors: A retrospective study of 129 cases.

“…There have been several studies reporting differences in the frequency and distribution of minor salivary gland tumors (1)(2)(3)(4)(5)(6)(7)(8)(9). The purpose of this study was to determine the relative frequency and intraoral location of benign and malignant tumors of minor salivary glands in certain Japanese population groups (Kanto districts) and to provide data for comparison with other epidemiological findings in different geographic locations worldwide.…”

Carcinoma in Pleomorphic Adenoma of the Tongue: Report of a case.

“…It occurs most often in the parotid and submandibular glands of the major salivary glands in elderly people (1), and occasionally occurs in the minor salivary gland, particularly in the palate (2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15).…”