Intraoral myoepithelial tumors: A review and case reports

Abdominal myoepithelial carcinoma: A rare abdominal wall entity of an uncommon tumor

“…This feature contrasts with ME carcinomas of the salivary gland, where the most significant feature of malignancy is infiltration and invasive growth [1] , [5] . In their comprehensive study, Hornick and Fletcher emphasized that in the setting of severe cytological atypia, there was a statistically significant difference in metastasis and recurrence, elucidating the link to aggressive behavior [4] , [8] , [15] .…”

“…Other markers which may be identified are SMA, Calponin and p63. Frequently, myogenic markers may be lost, but this does not rule out ME tumors, as it is well established that neoplastic myoepithelial cells often lose expression of myogenic markers [4] .…”

“…Myoepithelial carcinoma, or malignant myoepithelioma, was first studied by Stromeyer et al in 1975 [3] . These tumors show a wide range of cytological variations, including spindle, plasmacytoid, epithelioid, and clear cell type [4] . The relatively better-known site of origin of these rare tumors is the salivary glands, with the parotid gland leading the board [3] ; however, even here, their incidence accounts for less than 1 % of all salivary gland tumors [3] , [4] .…”

Prevalence of Benign Anorectal Diseases: A huge burden on society

“…Due to this, majority of them suffer from interminable morbidity for rest of their life 3,12 . Kulkarni et al 8 has observed that majority of these patients are too bashful to talk about their complications or to get consultation from surgeon well in time until they are in dejected circumstances and sometimes ending up in major morbidities like permanent colostomies. At the other end, the quacks or hakeem responsible hardly have any guilt about their malpractice, rather they tout it as one of the ways of their social services.…”

“…After treatment, some shows contentment to their symptoms and believe that their problem is resolved up to some extent. But majority of these have to regret for life, because their original disease or symptoms gets worse or complicated and they have to pay the high price in rest of life for getting out of such complications 1,8 . This study is planned with a view to observe and highlight the burgeoning worst outcomes of benign anorectal disease in our patients which if treated timely and rightly can be reduced.…”