Intraoral North American blastomycosis

Mincer, Harry H.; Oglesby, Richard J.

doi:10.1016/0030-4220(66)90138-1

Cited by 16 publications

(9 citation statements)

References 3 publications

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“…Blastomycosis is a deep mycotic infection, caused by Blastomyces dermatitidis, found mainly in North America, particularly in rural Mississippi, Ohio and Missouri River basins as well as the Great Lakes region (18, 38). In humans, blastomycosis presents as pulmonary, disseminated or localized cutaneous lesions (79). As in aspergillosis, the fungal spores are found in the soil and may initiate the disease when inhaled.…”

Section: Oral Manifestations Of Uncommon Systemic Mycosesmentioning

confidence: 99%

“…Oral lesions may arise through disseminated blastomycosis (81, 113). Oral blastomycosis is uncommon and may present as single or multiple ulcerations, sessile projections, and granulomatous or verrucous lesions (13, 79, 91, 98). In one study of 40 patients with balstomycosis, one‐quarter demonstrated oral or nasal lesions (133) and in another study, seven of ten patients had nonspecific oral ulcerations in addition to systemic disease (13).…”

Section: Oral Manifestations Of Uncommon Systemic Mycosesmentioning

confidence: 99%

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Oral mucosal fungal infections

Samaranayake¹,

Leung²,

Li³

2008

Periodontology 2000

219

222

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Section: Oral Manifestations Of Uncommon Systemic Mycosesmentioning

confidence: 99%

Section: Oral Manifestations Of Uncommon Systemic Mycosesmentioning

confidence: 99%

Oral mucosal fungal infections

Samaranayake¹,

Leung²,

Li³

2008

Periodontology 2000

219

222

View full text Add to dashboard Cite

“…Blastomycosis is a deep mycotic infection caused by Blastomyces dermatitidis , found mainly in North America, particularly in the rural Mississippi, Ohio, and Missouri River basins as well as the Great Lakes region (69,75). In humans, blastomycosis presents as either pulmonary, disseminated, or localized cutaneous lesions (76). As in aspergillosis, the fungal spores are found in the soil and may initiate the disease when inhaled.…”

Section: Oral Manifestations Of Uncommon Systemic Mycosesmentioning

confidence: 99%

“…Oral lesions may arise through disseminated blastomycosis (65,77). Oral blastomycosis is uncommon and may present as single or multiple ulcerations, sessile projections, and granulomatous or verrucous lesions (76,78–80). In a study of 40 patients with blastomycosis, one‐quarter demonstrated oral or nasal lesions (81).…”

Section: Oral Manifestations Of Uncommon Systemic Mycosesmentioning

confidence: 99%

Candidiasis and other fungal diseases of the mouth

2002

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The advent of the human immunodeficiency virus (HIV) and the increasing prevalence of immunocompromised individuals due to surgical and medical advances have resulted in a resurgence of opportunistic infections including oral candidiasis and other rare mycoses which were once considered exotic. It is now recognized that oral candidiasis may present in many clinical guises that may confound the unwary clinician. Other mycotic diseases such aspergillosis, cryptococcosis, histoplasmosis, and mucormycosis may manifest intraorally both as primary lesions and as secondary manifestation of systemic disease. The primary oral pathology of most of the latter mycoses is ulcerations that respond well to systemic therapy with the polyene, amphotericin B. In general, the management of oral fungal infections has been revolutionized by the triazole group of drugs, fluconazole and itraconazole, although recent reports indicate an alarming increase of resistant organisms in particular to fluconazole. The first part of this review attempts to provide an overview of clinical variants of oral candidiasis and current therapeutic techniques, while the latter part outlines the rare oral mycoses and their management.

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“…We reviewed 5 cases of mandibular blastomycosis in North America and summarized their characteristics in the Table. [13][14][15][16][17] In a similar fashion to our patient, most of the patients in the review presented with tooth pain and mandibular swelling. Four of these patients were from the United States, 1 from Canada, and the other from an unknown region of North America.…”

Section: Discussionmentioning

confidence: 66%

Mandibular blastomycosis: A case report and review of the literature

Albarillo

Varma

MacLeod

2018

Germs

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Introduction Blastomycosis is an endemic mycosis in the United States known to primarily cause pneumonia. However, dissemination to different organs including the musculoskeletal system has been described. Case report We report a case of mandibular blastomycosis in a healthy patient with no evidence of lung involvement. A 28 year-old female presented with recurrent right mandibular osteomyelitis despite courses of antibiotics and surgical debridement. She eventually underwent right hemimandibulectomy. Budding yeasts visualized on Gomori Methenamine-Silver (GMS) and Periodic acid-Schiff (PAS) were morphologically consistent with Blastomyces dermatitidis, and intra-operative cultures showed growth of mold identified as B. dermatitidis by DNA probe. She was placed on a prolonged course of itraconazole with clinical improvement. We also reviewed the literature and found 5 cases of similar presentation which we briefly summarized in this present case report. Conclusion Blastomycosis should be considered in patients with recurrent or persistent mandibular osteomyelitis even in immunocompetent individuals.

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Intraoral North American blastomycosis

Cited by 16 publications

References 3 publications

Oral mucosal fungal infections

Oral mucosal fungal infections

Candidiasis and other fungal diseases of the mouth

Mandibular blastomycosis: A case report and review of the literature

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