Intraoral photobiomodulation-induced orthodontic tooth alignment: a preliminary study

Objective: This systematic review of published research evaluates the parameters and reported outcomes in photobiomodulation therapies (PBMTs) used in management of pain and accelerated tooth movement during orthodontic treatment. Background: Consequent to positive in vitro and animal studies, there has been considerable interest in the potential applications of PBMT to ameliorate pain and to accelerate orthodontic tooth movement. Due to the lack of consistency of wavelengths and parameters applied, there is as yet no consensus in respect of guidance for clinical use. Within the limitations of the reported literature, a digest of key outcomes and parameters is presented here to assist researchers and interested clinicians. Materials and methods: Search engines, PubMed, Google Scholar, and Cochrane, were applied to identify clinical investigations into the potential benefits of PBMTs in orthodontic management. Keywords used were ''low-level laser therapy,'' ''low-level light therapy,'' ''photobiomodulation,'' ''orthodontics,'' ''pain,'' ''tooth movement,'' and ''randomized clinical trial ‡5 years.'' A total of 35 articles were identified, covering the 5-year period January 2013 to December 2018. Only human clinical trials were considered. Seventeen articles were included in this investigation and the reported parameters and outcomes were assessed and presented for comparison. Results: Seven of nine studies supported the effectiveness of PBMT to reduce or prevent pain. There was no consensus on choice of wavelength and a range of parameters were found beneficial. Of the seven tooth movement studies included, four of the seven were positive, of which two used a home-use light-emitting diode (LED) device, as opposed to a clinician-applied laser. A variety of wavelengths and parameters were found to be effective in accelerating tooth movement in the range of 20-40% compared with control. Conclusions: Due to a lack of consistency in approach, further studies are required to achieve a high level of acceptance. The clinical logistics associated with frequent applications supports the concept of patient home delivery use of LED devices, although there are insufficient studies at present to make an evidence-based determination of this type of appliance. To gain more general professional acceptance of the use of PBMT in orthodontics, a continued effort to extend the number of quality human clinical trials is required. Based on the current evidence base, further positive onward progression can be regarded as inevitable.

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“…It is hoped that this newer intraoral device may be subject to future well-designed and constructed clinical trials. 58…”

Section: Pbmt: Accelerated Otmmentioning

confidence: 99%

Systematic Review of Orthodontic Treatment Management with Photobiomodulation Therapy

Cronshaw

Parker

Anagnostaki

et al. 2019

Photobiomodulation, Photomedicine, and Laser Surgery

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“…The increased demand for rapid orthodontic treatment has led to the introduction of several methods, which also reduce potential risks of dental and periodontal complications such as external apical root resorption, high levels of dental caries, and subsequent gingivitis and periodontitis [3][4][5]. Some of the proposed methods are adequate use of brackets, controlling force levels, and relying on less friction bracket systems, photobiomodulation, pharmacological approaches, or low-intensity laser irradiation [6][7][8][9][10][11]. However, irrespective of the method, the rate of the tooth movement is dictated by the biologic response to the applied orthodontic forces [2,12].…”

Section: Introductionmentioning

confidence: 99%

Effect of mini-screw-facilitated micro-osteoperforation on the rate of orthodontic tooth movement: a single-center, split-mouth, randomized, controlled trial

2020

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Objective: The present study aimed to evaluate the effect of MOP over a 3-month period and to determine the influence of the number of perforations on the rate of canine retraction. In addition, the amount of pain and discomfort caused by the MOP method was evaluated. Trial design: A single-center, split-mouth, triple-blind, randomized, controlled trial was conducted. Methods: The clinical trial was conducted from December 2018 to July 2019 in the Orthodontic Clinic, Shiraz Dental School. Twenty-eight patients (range from16.3 to 35.2 years) who need fixed orthodontic treatment were recruited and randomly assigned to MOP1 and MOP2 groups. In each patient one side of the mouth worked as a control side which received no MOPs. Four months after first premolars extraction, patients in MOP1 group received 3 MOPs on the buccal surface of alveolar bone in the experimental side to accelerate canine retraction whereas patients in MOP2 group received 3 buccal MOPs and 3 palatal MOPs in the experimental side. The amount of canine retraction was measured every 28 days at three intervals on both sides of the mouth. Pain perception was also measured on the day of MOP procedure and subsequently at 24 h. Randomization was performed using online software RANDOM.ORG; the recruited patients were divided into two parallel groups with a 1:1 allocation ratio then the side of MOPs intervention in each subject was randomly determined with coin tossing. Triple blinding design was employed. Results: The result of the intra-examiner reliability using ICC was 0.97 (P < 0.001), indicating excellent repeatability and reliability of the measurements. The baseline characteristics between the groups were similar (P > 0.05). There was a significant difference in the rate of canine retraction between the MOP groups and the contralateral control sides, as well as between the MOP1 and MOP2 groups (P < 0.05). Conclusion: The MOP procedure was effective in accelerating orthodontic tooth movement, although the amount of acceleration was not clinically significant in the case of canine retraction. An increase in the number of MOPs resulted in a significant acceleration of the canine retraction. Trial registration: The trial was registered 30 November 2018 at the Iranian Registry of Clinical Trials (IRCT20181121 041713N1).

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“…The evidence regarding PBM is limited to one trial using the OrthoPulse™ appliance which was conducted by a consulting orthodontist for the company (Biolux Research Ltd.). The study concluded that intraoral PBM increased the average rate of tooth movement resulting in a 54 per cent average decrease in alignment duration compared with a control . However, there were confounding variables including the use of different brackets in the two test groups.…”

Section: Non‐surgical Methodsmentioning

confidence: 95%

Accelerated orthodontic treatment ‐ what's the evidence?

Miles

2017

Australian Dental Journal

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The demand and accessibility of orthodontic care has increased but has also been accompanied by patient requests for shorter treatment times. Longer orthodontic treatment increases the risk of decalcification, gingival recession, and root resorption and so shorter treatment times have multiple advantages as well as appealing to patient's desires. Numerous techniques and materials have been suggested to reduce treatment times but, in most cases, are based upon selected case reports with no prospective clinical trials to validate claims. The present review examines many of the current options purported to accelerate orthodontic tooth movement and the level of evidence presently available. There is some evidence to suggest that low-level laser therapy and a corticotomy involving the raising of a muco-periosteal flap are associated with accelerated orthodontic tooth movement; however, the current level of evidence is low to moderate in quality. For this reason, further research is required before routine application could be recommended.

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Intraoral photobiomodulation-induced orthodontic tooth alignment: a preliminary study

Cited by 52 publications

References 51 publications

Systematic Review of Orthodontic Treatment Management with Photobiomodulation Therapy

Systematic Review of Orthodontic Treatment Management with Photobiomodulation Therapy

Effect of mini-screw-facilitated micro-osteoperforation on the rate of orthodontic tooth movement: a single-center, split-mouth, randomized, controlled trial

Accelerated orthodontic treatment ‐ what's the evidence?

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